Micronized Phytosome Supplement Composition for Higher Bioavailability
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Solution Overview
Problem
Common dietary supplements such as DHEA derivatives, NEFAs, L-arginine, EAAs, HMB free acids, trans-resveratrol, adaptogens, water-soluble and fat-soluble vitamins face challenges of poor bioavailability and low efficacy when taken individually, leading to adverse effects and reduced nutritional benefits.
Innovation Solution
A multi-bioavailability delivery system utilizing micronization, phytosome technology, and cyclodextrin complexation enhances the absorption of these supplements by reducing particle size, forming complexes, and targeting specific tissues, thereby increasing efficacy and reducing dosage requirements.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If high doses of supplements are taken to improve efficacy, then nutritional benefits increase, but adverse effects and toxicity increase
Solution Approach 1:
The patent changes the physical and chemical parameters of the supplements by micronizing particles to reduce size and increase surface area, complexing with cyclodextrins to improve solubility, and incorporating into phytosome formulations to enhance absorption. These parameter changes enable effective dosing at lower concentrations, reducing adverse effects while maintaining nutritional benefits.
Solution Approach 2:
The patent introduces intermediary substances including cyclodextrin complexes as carriers and phytosome formulations as absorption enhancers. These intermediaries facilitate the transport and absorption of active ingredients, improving bioavailability without requiring high doses that cause toxicity.
2Ease of operation
If supplements are taken individually to maintain simplicity, then ease of use is maintained, but bioavailability and efficacy are reduced
Solution Approach 1:
The patent merges multiple supplements into integrated formulations where micronized particles, cyclodextrin complexes, and phytosome formulations are combined in single capsule or tablet products. This combining approach maintains ease of use while significantly improving bioavailability and efficacy through synergistic effects and enhanced absorption mechanisms.
3Reliability
If particle size of supplements is reduced to improve absorption, then bioavailability increases, but manufacturing complexity increases
Solution Approach 1:
The patent applies micronization technology to change the particle size parameter of supplements from conventional sizes to fine particles less than 10 micrometers. This parameter change dramatically improves bioavailability and absorption while the micronization process itself is an established manufacturing technique that can be integrated into existing production lines.
Solution Approach 2:
The patent creates composite materials by combining micronized particles with cyclodextrin complexes and phytosome formulations. These composite structures enhance absorption and bioavailability while consolidating multiple functional components into a single manufacturable product that can be produced using standard pharmaceutical manufacturing processes.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The system significantly improves the nutritional effects of supplements by enhancing bioavailability, minimizing side effects, and achieving synergistic benefits for muscular hypertrophy, physical performance, and overall health benefits.
Implementation Method 1
A multi-bioavailability delivery system utilizing micronization, phytosome technology, and cyclodextrin complexation enhances the absorption of these supplements by reducing particle size
Implementation Method 2
A multi-bioavailability delivery system utilizing micronization, phytosome technology, and cyclodextrin complexation enhances the absorption of these supplements
Implementation Method 3
A multi-bioavailability delivery system utilizing micronization, phytosome technology, and cyclodextrin complexation enhances the absorption of these supplements
Data Source
AI summary
A method of forming a DHEA derivative supplement including adaptogens, modified stilbenoids complex, non-esterified omega-3 fatty acids, essential amino acids, HMB free acid, vitamins, L-arginine, creatine, green tea extracts, and chelated minerals, in a multi-bioavailability delivery system, based on the nature of the constituents, formed as an encapsulated micronized material having a phytosomal delivery system which reduces supplements dosage while increasing active nutrients efficacy and bioavailability by providing a targeted delivery system for nutritional effects.