Implantable Micropump Drainage System for Interstitial Fluid Management

Resolve Bottlenecks,
Find Innovative Solutions
Generate Solutions

Solution Overview

Problem

Current medical systems are unable to effectively absorb and transport fluids distributed in the interstitium, such as in cases of edema, directly to the bloodstream or lymphatic system, leading to chronic swelling and disability in conditions like lymphedema.

Innovation Solution

A minimally invasive, implantable drainage system comprising controllable micropumps and porous elements that emulate the natural lymphatic system's function, actively absorbing fluid from multiple openings and transporting it to a desired location, such as a vein or lymphatic duct, using a controller to coordinate the sequential activation of micropumps for peristalsis-based drainage.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If conventional drainage systems are used, then fluid can be drained from a single location, but they are unable to effectively absorb and transport fluids distributed in the interstitium

Engineering Contradiction:
Improvefluid absorption efficiencyVSAvoidsystem structure
Core Design Contradiction:
ProductivityVSDevice complexity

Solution Approach 1:

The drainage system is divided into multiple independent micropumps distributed along the interstitial space, each capable of absorbing fluid locally. This segmentation allows the system to effectively drain distributed fluid accumulation while maintaining manageable individual pump units

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

Multiple porous elements with multiple openings are nested within the drainage system structure, allowing fluid to be absorbed through multiple access points simultaneously. The nested configuration enables comprehensive interstitial fluid collection without proportionally increasing system complexity

Inventive Principle:
Principle #7Nested doll (Nesting)

2Productivity

If multiple micropumps are used to drain distributed fluid, then fluid absorption efficiency improves, but device complexity increases

Engineering Contradiction:
Improvefluid transport capacityVSAvoidnumber of components
Core Design Contradiction:
ProductivityVSDevice complexity

Solution Approach 1:

Multiple micropumps are connected in series to form an integrated drainage system, merging their individual fluid transport capacities into a unified flow path. This combining approach increases overall productivity while managing complexity through systematic integration

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The drainage system is designed with universal porous elements that can be configured in different numbers and arrangements to treat various types of distributed fluid accumulation. This multi-functionality allows the same basic structure to adapt to different clinical scenarios without requiring entirely different system designs

Inventive Principle:
Principle #6Universality (Multi-functionality)

3Reliability

If continuous drainage is implemented, then tissue fluid homeostasis is maintained, but energy consumption increases

Engineering Contradiction:
Improvehomeostasis maintenanceVSAvoidpump energy consumption
Core Design Contradiction:
ReliabilityVSUse of energy by moving object

Solution Approach 1:

The micropumps are activated in sequential periods rather than continuously, creating a wave-like drainage pattern that maintains effective fluid removal while allowing energy-saving intervals. This periodic operation preserves tissue fluid homeostasis through consistent drainage cycles

Inventive Principle:
Principle #19Periodic action

Solution Approach 2:

While individual pumps operate periodically, the series configuration ensures continuous useful action as one pump operates while others are in their energy-saving phase. This continuity maintains reliable fluid homeostasis without requiring all pumps to run simultaneously, thereby reducing total energy consumption

Inventive Principle:
Principle #20Continuity of useful action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This system maintains tissue fluid homeostasis, reduces the need for recurring treatments, minimizes aesthetic impairment, and prevents limb infections by continuously draining excess fluid, offering a more effective solution for conditions like lymphedema and chronic edema.

Implementation Method 1

The pumps are activated in an intermitted, asynchronous manner, so that they create peristaltic pressure waves along the tubular members

Methodology Applied
Scientific EffectPeristalsis: Peristalsis

Implementation Method 2

N-1 porous elements implanted in the edematous space, connecting the N pumps in series... characterized by access pores distributed along their surface

Methodology Applied
Scientific EffectCapillary action: Capillary Action

Data Source

PatentEP3204101B1Medical fluid drainage system
Publication Date: 2022.06.08 ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL)
  • EP3204101B1 patent drawingFigure 1A~1C
  • EP3204101B1 patent drawingFigure 2A~2B
  • EP3204101B1 patent drawingFigure 3

AI summary

A medical fluid drainage system which may be advantageously used to actively absorb excess fluid from an interstitium in a living host and to transport it from an inlet member 1 in a non edematous body part out of an outlet member 4 via pumps (5, 6, 7) built in series, such as a distal area with functional lymphatic vessels, or directly in a lymphatic vessel, or directly in a blood vessel.