Microscope Camera Mode Selection for Image Quality and Frame Rate

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Solution Overview

Problem

Microscope systems with digital cameras face delays and image quality issues due to large data volumes, limited frame rates, and noise when trying to balance exposure time and gain for low-luminance specimens, making interactive microscopy challenging and inconvenient for both navigation and documentation.

Innovation Solution

A microscope system where at least one setting element is connected to the camera to automatically set a specific image mode based on microscope modifications, such as stage position, objective selection, diaphragm settings, and illumination, allowing for optimized image modes that adjust exposure time, gain, and illumination intensity, ensuring consistent image format and quality.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If long exposure time is used for low-luminance specimens, then image quality is improved, but frame rate is limited

Engineering Contradiction:
Improveimage qualityVSAvoidframe rate
Core Design Contradiction:
Measurement precisionVSSpeed

Solution Approach 1:

The system dynamically adjusts camera settings including exposure time, gain, and image mode based on real-time microscope settings and specimen conditions. This allows the system to optimize between image quality and frame rate by adapting parameters rather than using fixed settings.

Inventive Principle:
Principle #15Dynamics

Solution Approach 2:

The patent changes multiple camera parameters simultaneously (exposure time, gain, binning mode, subsampling) to achieve optimal image quality for low-luminance specimens while maintaining acceptable frame rates. By adjusting these parameters in combination, the system resolves the contradiction between long exposure needs and frame rate requirements.

Inventive Principle:
Principle #35Parameter changes

2Speed

If short exposure time is used for navigation, then frame rate is improved, but image noise increases due to high gain

Engineering Contradiction:
Improveframe rateVSAvoidimage noise
Core Design Contradiction:
SpeedVSObject-generated harmful factors

Solution Approach 1:

The system dynamically switches between different image modes (navigation mode, documentation mode, low-luminance mode) based on the current microscope setting and operational requirements. This dynamic switching allows optimal frame rate for navigation while minimizing noise through appropriate gain and mode selection.

Inventive Principle:
Principle #15Dynamics

Solution Approach 2:

The camera system is designed with multiple image modes that serve different functions (navigation, documentation, low-luminance imaging). Each mode is optimized for its specific purpose, allowing the system to achieve high frame rates for navigation while having separate optimized modes for quality documentation, thus resolving the noise-frame rate contradiction.

Inventive Principle:
Principle #6Universality (Multi-functionality)

3Measurement precision

If different image modes are selected for various microscope settings, then image optimization is improved, but image consistency deteriorates

Engineering Contradiction:
Improveimage optimizationVSAvoidimage consistency
Core Design Contradiction:
Measurement precisionVSStability of the object's composition

Solution Approach 1:

The system establishes feedback connections between microscope settings and camera image mode selection. When microscope settings change (stage position, objective, diaphragm, illumination), the system automatically selects the appropriate image mode to maintain optimal image quality while ensuring consistency through automated control rather than manual mode switching.

Inventive Principle:
Principle #23Feedback

Solution Approach 2:

The system pre-defines multiple image modes with optimized settings for different microscope configurations and specimen types. Based on the current microscope setting, the system automatically selects the pre-optimized mode, ensuring both image optimization and consistency without requiring real-time manual adjustment.

Inventive Principle:
Principle #10Preliminary action

4Measurement precision

If digital camera is used for high resolution, then image quality is improved, but interactive work delays occur due to large data volumes

Engineering Contradiction:
Improveimage qualityVSAvoidinteractive work delays
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The system dynamically adjusts the balance between image resolution and data transmission speed based on the current operational mode. In navigation mode, it uses optimized settings that reduce data volume for faster interaction, while in documentation mode, it maximizes resolution. This dynamic adaptation resolves the contradiction between high quality and interactive responsiveness.

Inventive Principle:
Principle #15Dynamics

Solution Approach 2:

The patent segments the imaging task into different modes (navigation, documentation, low-luminance) with optimized settings for each. This segmentation allows the system to use high-resolution settings only when necessary for documentation, while using optimized lower-data-volume settings for navigation, thus reducing overall interactive delays while maintaining quality when needed.

Inventive Principle:
Principle #1Segmentation

Data Source

PatentUS7986338B2Microscope system and image production method
Publication Date: 2011.07.26 LEICA MICROSYSTEMS CMS GMBH
  • US7986338B2 patent drawing
  • US7986338B2 patent drawing
  • US7986338B2 patent drawing

AI summary

A microscope system and an image production method utilizing a microscope having one or more setting elements for modifying at least one microscope setting, and a camera for acquiring a microscope image, which camera is operable in predeterminable image modes. At least one of the setting elements of the microscope is operatively connected to the camera in such a way that a specific image mode of the camera is settable as a function of a modification of the microscope setting. Alternatively or additionally, a microscope setting can be modified as a function of an image mode of the camera that is present.