Microscope Image Analysis System with Pre-Configured Acquisition

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Solution Overview

Problem

Current image-based analysis methods face challenges in efficiently processing the large amounts of data required for insightful results, often necessitating significant time and IT resources.

Innovation Solution

The method involves determining two sets of requirements: one for image acquisition and another for analysis, allowing for targeted image capture and efficient data reduction, which can be further analyzed using machine learning algorithms for enhanced insights.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If comprehensive image data is captured for thorough analysis, then diagnostic accuracy is improved, but data processing time and IT resources increase

Engineering Contradiction:
Improvediagnostic accuracyVSAvoiddata processing time
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The system performs preliminary actions by determining analysis requirements before image acquisition, configuring the imaging device to capture only necessary images with appropriate parameters. This pre-planning ensures diagnostic accuracy is maintained while avoiding unnecessary data collection that would increase processing time.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The system extracts and separates essential analysis requirements from comprehensive imaging protocols. By identifying and capturing only the specific images needed for the determined analysis type, the system removes redundant data processing steps while preserving diagnostic accuracy.

Inventive Principle:
Principle #2Taking out (Extraction)

2Measurement precision

If comprehensive image data is captured for thorough analysis, then diagnostic accuracy is improved, but IT resources required increase

Engineering Contradiction:
Improvediagnostic accuracyVSAvoidIT resources
Core Design Contradiction:
Measurement precisionVSQuantity of substance

Solution Approach 1:

The system determines analysis requirements and configures imaging parameters before acquisition, ensuring that only necessary images are captured. This preliminary configuration reduces the quantity of image data requiring IT resources for storage and processing while maintaining diagnostic accuracy.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The system extracts essential imaging requirements from comprehensive protocols, capturing only the specific subset of images needed for the determined analysis type. This extraction reduces the overall data volume and corresponding IT resource requirements while preserving diagnostic capability.

Inventive Principle:
Principle #2Taking out (Extraction)

3Measurement precision

If continuous imaging is performed for complete temporal analysis, then temporal pattern detection is improved, but phototoxicity to specimen increases

Engineering Contradiction:
Improvetemporal pattern detectionVSAvoidphototoxicity
Core Design Contradiction:
Measurement precisionVSObject-affected harmful factors

Solution Approach 1:

The system implements periodic imaging at strategically determined time intervals based on the analyzed requirements, rather than continuous imaging. This periodic approach captures sufficient temporal patterns while minimizing cumulative light exposure and phototoxicity to the specimen.

Inventive Principle:
Principle #19Periodic action

Solution Approach 2:

The system determines temporal analysis requirements before imaging, configuring the acquisition schedule to capture only the necessary time points for detecting temporal patterns. This preliminary planning reduces unnecessary imaging events and associated phototoxicity.

Inventive Principle:
Principle #10Preliminary action

Data Source

PatentUS20250045919A1Computer-based methods for analyzing a plurality of images, diagnostic and medical devices, and GUI
Publication Date: 2025.02.06 LEICA MICROSYSTEMS CMS GMBH
  • US20250045919A1 patent drawing
  • US20250045919A1 patent drawing

AI summary

A first aspect of this disclosure is related to a method for analyzing images, comprising the steps determining a first set of requirements, obtaining a plurality of images of a specimen from an imaging device, in particular in a microscope, based on the first set of requirements, obtaining a second set of requirements, analyzing the specimen from the plurality of images based on the second set of requirements.