Microscope Image Anonymization for Privacy-Safe ML Training

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Solution Overview

Problem

The challenge is to make microscope images with sensitive information usable for image processing, such as training machine learning applications, while maintaining data privacy by anonymizing sensitive content.

Innovation Solution

A method and system that identify and render unrecognizable specific image sections with sensitive information within microscope images using image processing programs, allowing the remaining content to be exploited for further processing steps.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Loss of information

If microscope images containing sensitive information are shared for training machine learning programs, then the quality and comprehensiveness of training data is improved, but data privacy and confidentiality are compromised

Engineering Contradiction:
Improvetraining data qualityVSAvoiddata privacy risk
Core Design Contradiction:
Loss of informationVSObject-affected harmful factors

Solution Approach 1:

The patent extracts and removes sensitive information (such as patient identifiers, sample labels, and metadata) from microscope images while preserving the remaining image content. This extraction process separates useful training data from harmful sensitive information, allowing the images to be shared for machine learning training without compromising privacy.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The patent applies different processing treatments to different regions of the image: sensitive information regions are anonymized or removed, while non-sensitive regions retain their original quality and detail. This local differentiation allows maximum preservation of useful image data while eliminating privacy risks in specific sensitive areas.

Inventive Principle:
Principle #3Local quality

2Object-affected harmful factors

If sensitive information is completely removed from microscope images through manual editing, then data privacy is protected, but the efficiency and scalability of image processing is reduced

Engineering Contradiction:
Improvedata privacy protectionVSAvoidimage processing efficiency
Core Design Contradiction:
Object-affected harmful factorsVSProductivity

Solution Approach 1:

The patent replaces manual mechanical editing processes with automated computational methods. Machine learning algorithms and image processing software automatically identify, classify, and anonymize sensitive information in microscope images, eliminating the need for time-consuming manual review and editing while maintaining high privacy protection standards.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The system enables self-service automated anonymization where the image processing program autonomously identifies sensitive information and applies appropriate anonymization techniques without requiring continuous human intervention. This self-acting system dramatically improves processing efficiency while maintaining consistent privacy protection.

Inventive Principle:
Principle #25Self-service

3Loss of information

If comprehensive training data from multiple sources is collected, then the performance of machine learning programs is improved, but the complexity of data management and coordination increases

Engineering Contradiction:
Improvetraining data comprehensivenessVSAvoiddata management complexity
Core Design Contradiction:
Loss of informationVSDevice complexity

Solution Approach 1:

The patent creates a universal anonymization framework that can process microscope images from multiple different sources and institutions using a single standardized approach. The system handles various types of sensitive information (patient data, sample identifiers, institutional metadata) through unified processing protocols, enabling seamless aggregation of training data from diverse sources without increasing management complexity.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Data Source

PatentUS12056908B2Microscopy system, method and computer program for processing microscope images
Publication Date: 2024.08.06 CARL ZEISS MICROSCOPY GMBH
  • US12056908B2 patent drawing
  • US12056908B2 patent drawing
  • US12056908B2 patent drawing

AI summary

A method for processing microscope images comprises: acquiring a microscope image captured by a microscope; identifying at least one image section with sensitive information within the microscope image by means of an image processing program which uses provided reference information regarding sensitive information; rendering unrecognizable the at least one identified image section with sensitive information in order to generate an anonymized image; and outputting the anonymized image.