Microscope System with Automated Culture Condition Image Association

Resolve Bottlenecks,
Find Innovative Solutions
Generate Solutions

Solution Overview

Problem

Researchers face challenges in identifying the cause of differences between expected and observed images of culture cells, as various factors such as the culture cell itself, the microscope, and surrounding environments can influence the results, making it difficult to manage and analyze culture conditions effectively.

Innovation Solution

A microscope system and culture-cell analysis system that includes a microscope apparatus and a control device to record microscopic images and culture conditions in association with each other, allowing for easy identification of influencing factors and reducing user labor in data association.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Loss of information

If researchers manually manage and associate culture conditions with microscopic images, then they can maintain detailed records, but the workload increases and efficiency decreases

Engineering Contradiction:
Improveculture condition dataVSAvoiddata association efficiency
Core Design Contradiction:
Loss of informationVSProductivity

Solution Approach 1:

The patent merges the culture monitoring system with the microscope system, allowing both culture condition data and microscopic image data to be collected and associated automatically through a unified control device, eliminating manual data association workflows

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The system enables self-service data association by automatically linking culture condition parameters with microscopic images through time-synchronized data collection, where the control device autonomously correlates data without requiring researcher intervention

Inventive Principle:
Principle #25Self-service

2Reliability

If multiple factors influencing culture cell observations are monitored separately, then comprehensive data can be collected, but the complexity of data management increases

Engineering Contradiction:
Improveobservation accuracyVSAvoiddata management system
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The control device is designed with multi-functionality, serving both as a culture condition monitor and a microscope control unit, thereby collecting diverse data types (temperature, CO2 levels, images) through a single integrated system rather than multiple separate devices

Inventive Principle:
Principle #6Universality (Multi-functionality)

Solution Approach 2:

The control device acts as an intermediary that standardizes and harmonizes data from different sources (culture monitoring sensors and microscope imaging system), converting diverse data formats into a unified structure that simplifies subsequent analysis

Inventive Principle:
Principle #24Intermediary (Mediator)

Data Source

PatentUS10877259B2Microscope system, culture-cell analysis system, and method of managing microscopic image
Publication Date: 2020.12.29 EVIDENT CORP
  • US10877259B2 patent drawing
  • US10877259B2 patent drawing
  • US10877259B2 patent drawing

AI summary

A microscope system includes a microscope apparatus configured to obtain a microscopic image of a culture cell by picking up an image of the culture cell, and a first control device configured to record a culture condition of the culture cell and the microscopic image in a recording unit in association with each other.