Microscope Lens Alignment Device for Fermentation Monitoring
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Solution Overview
Problem
Existing optical adjustment systems for cellular fermentation tanks suffer from angular errors, cumbersome assembly, and low accuracy due to the lack of a clamping device for the lens barrel and mismatched interfaces between the microscope and illumination components, leading to unstable cell recognition and image alignment.
Innovation Solution
A spatial posture adjusting device with a base frame, up/down adjustment table, load plate, microscope adjustment mechanism, and illumination rotation adjustment mechanism, featuring a three-axis revolving mandrel and high-precision joint bearing, clamping device, and motorized screws for precise angular and positional adjustments to align the optical axis with the cells.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Ease of manufacture
If a commercial optical adjustment frame is used without a clamping device, then the lens barrel can be connected in a transitional manner, but this leads to angular error between the optical axis and the reference plane of the adjustment table
Solution Approach 1:
The device is divided into independent functional modules: the optical adjustment frame for angular adjustment, the mechanical adjustment table for positional adjustment, and the clamping device for secure mounting. Each module performs a specific function, allowing precise angular adjustment of the lens barrel while maintaining manufacturing simplicity through modular assembly.
Solution Approach 2:
The clamping device is designed to preliminarily clamp the lens barrel in the correct position before final adjustment. This preliminary positioning action ensures that the lens barrel is securely held at the correct angle, preventing angular error during subsequent adjustments and eliminating the need for transitional connections.
2Ease of operation
If the optical adjustment frame and mechanical adjustment table are assembled together, then the monitoring system can be adjusted, but the assembly is cumbersome and unstable
Solution Approach 1:
The optical adjustment frame and mechanical adjustment table are merged into a single integrated device with a unified structure. The frame is directly mounted on the adjustment table, eliminating the need for separate assemblies and reducing overall complexity. This integration maintains full adjustment capability while simplifying the assembly process and improving stability.
3Ease of operation
If the optical adjustment frame and mechanical adjustment table are assembled together, then the monitoring system can be adjusted, but the assembly has poor accuracy due to redundancy in spatial dimension adjustment
Solution Approach 1:
The adjustment functions are segmented into distinct domains: the optical adjustment frame handles angular adjustments (pitch and yaw), while the mechanical adjustment table handles positional adjustments (x, y, z coordinates). This segmentation eliminates redundancy by assigning each adjustment degree of freedom to the most appropriate mechanism, thereby improving overall adjustment accuracy.
Solution Approach 2:
The device incorporates dynamic adjustment capabilities with multiple degrees of freedom. The optical adjustment frame provides angular dynamics for precise orientation control, while the mechanical adjustment table provides positional dynamics. This dynamic design allows independent optimization of each adjustment type, improving accuracy by preventing angle coupling and redundancy.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The device ensures accurate alignment of the microscope lens with the cells, providing a uniform light field and improving the accuracy of cell recognition and monitoring by allowing precise adjustments of the optical axis, including elevation and azimuth directions.
Implementation Method 1
the up/down adjustment table includes a first motor and a first sliding rail; the first motor is axially connected with a first screw
Implementation Method 2
the mobile platform includes a second motor; the second motor is axially connected with a second screw
Implementation Method 3
the three-axis revolving mandrel is axially connected to a joint bearing
Data Source
AI summary
The present invention discloses a spatial posture adjusting device for an optical axis of a microscopic monitoring system for a cellular fermentation tank. The adjusting device includes a base frame, where the base frame is fixedly provided with an up/down adjustment table; the up/down adjustment table is slidably connected to a load plate; the load plate is fixedly provided with a microscope adjustment mechanism and an illumination rotation adjustment mechanism in sequence; the illumination rotation adjustment mechanism includes a base; the base is fixedly connected to a first support frame; the first support frame is fixedly provided with an illuminator; the microscope adjustment mechanism includes a second support frame; the second support frame is fixedly provided with a clamping device; the clamping device is fixedly provided with a microscope device; the illumination rotation adjustment mechanism is fixedly connected with a mobile platform.


