Microscope Scanner Position Feedback for Distortion-Free Imaging

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Solution Overview

Problem

Current microscope scanners face issues with spatial distortions in digitized images due to fluctuations in sample movement velocity, leading to inefficient image capture and increased scan duration, as they rely on constant velocity assumptions rather than measured positions.

Innovation Solution

A microscope scanning apparatus with a detector array and a sample holder that moves relative to each other, controlled by a position monitoring system, allowing image capture at measured positions rather than assumed positions, enabling image capture during acceleration and deceleration phases and reducing the impact of external vibrations.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of operation

If image capture is triggered by assumed position based on constant velocity assumption, then the system is simpler to operate, but spatial distortions occur in the digitized image

Engineering Contradiction:
Improveease of operationVSAvoidspatial accuracy
Core Design Contradiction:
Ease of operationVSManufacturing precision

Solution Approach 1:

The system incorporates a position sensor that provides real-time feedback on the actual position of the sample holder. The controller uses this feedback information to trigger image capture at precisely the correct moments, eliminating spatial distortions while maintaining ease of operation. The feedback loop continuously monitors and adjusts the timing of image capture based on actual position rather than assumed position.

Inventive Principle:
Principle #23Feedback

2Device complexity

If the sample moves at constant velocity during scanning, then image capture timing is simpler, but velocity fluctuations cause images to occur at wrong locations

Engineering Contradiction:
Improvecontrol complexityVSAvoidposition accuracy
Core Design Contradiction:
Device complexityVSManufacturing precision

Solution Approach 1:

The position sensor continuously monitors the actual position of the sample holder and provides feedback to the controller. This feedback mechanism eliminates the need to assume constant velocity, as the system adapts to actual velocity variations in real-time. Image capture is triggered based on measured position feedback rather than predetermined timing based on assumed constant velocity.

Inventive Principle:
Principle #23Feedback

3Manufacturing precision

If the system waits for constant velocity before imaging, then spatial accuracy is improved, but scan duration increases due to dead-time

Engineering Contradiction:
Improvespatial accuracyVSAvoidscan duration
Core Design Contradiction:
Manufacturing precisionVSLoss of time

Solution Approach 1:

The position sensor begins monitoring the sample holder position from the start of the scan, including during acceleration and deceleration phases. The controller is ready to trigger image capture immediately when the correct position is reached, without waiting for constant velocity to be established. This preliminary monitoring eliminates dead-time while maintaining spatial accuracy through position-based triggering.

Inventive Principle:
Principle #10Preliminary action

4Stability of the object's composition

If external vibrations disturb the movement between sample holder and detector, then system stability deteriorates, but position-based triggering reduces the impact of these vibrations

Engineering Contradiction:
Improvesystem stabilityVSAvoidimage position accuracy
Core Design Contradiction:
Stability of the object's compositionVSManufacturing precision

Solution Approach 1:

The position sensor provides real-time feedback on the actual position of the sample holder, compensating for disturbances caused by external vibrations. The controller adjusts image capture timing based on this feedback, ensuring that images are captured at the correct positions even when vibrations cause deviations from the ideal motion path. This feedback mechanism reduces the impact of vibrations on image position accuracy.

Inventive Principle:
Principle #23Feedback

Data Source

PatentUS20240393576A1Method and apparatus for imaging a sample using a microscope scanner
Publication Date: 2024.11.28 VENTANA MEDICAL SYSTEMS INC
  • US20240393576A1 patent drawing
  • US20240393576A1 patent drawing
  • US20240393576A1 patent drawing

AI summary

A microscope scanning apparatus is provided comprising a detector array for obtaining an image from a sample and a sample holder adapted to hold the sample when in use and to move relative to the detector array along a scan path. A controller is further provided to monitor the position of the sample holder relative to the detector array and to trigger image capture by the detector array in accordance with said monitored position.