Microscope Slide Reactive Ion Etching Adhesion

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Solution Overview

Problem

Existing microscope slides require additional materials for improved adhesiveness, which can interfere with processes like dyeing and may cause section peeling, necessitating a solution that enhances adhesion without external coatings.

Innovation Solution

Introducing a structure with reactive ion etched unevenness on the surface of the microscope slide, similar to that found on polystyrene particles, to improve adhesiveness without additional materials, using reactive ion etching to create a hydrophilic surface with convex portions and recessed areas.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Strength

If a silane coating is applied to improve adhesiveness, then section peeling is prevented, but additional materials interfere with dyeing processes and may still cause peeling

Engineering Contradiction:
ImproveadhesivenessVSAvoidinterference with dyeing process
Core Design Contradiction:
StrengthVSObject-generated harmful factors

Solution Approach 1:

The invention extracts and removes the silane coating layer from the glass slide surface, replacing it with a physical surface structure (unevenness) that provides adhesiveness without chemical coatings. This eliminates the harmful interference with dyeing processes while maintaining the beneficial adhesion effect.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The invention changes the surface parameters of the glass slide by introducing controlled unevenness with specific height (0.01-10 μm) and area ratios (1-50%). This physical parameter modification provides adhesion through mechanical interlocking rather than chemical coating, avoiding interference with subsequent dyeing processes.

Inventive Principle:
Principle #35Parameter changes

2Strength

If additional materials are applied to enhance adhesion, then section attachment is improved, but the process complexity and potential for interference with microscopic observations increase

Engineering Contradiction:
Improvesection attachmentVSAvoidprocess complexity
Core Design Contradiction:
StrengthVSDevice complexity

Solution Approach 1:

The invention removes the need for additional coating materials by utilizing the glass slide's own surface structure. By creating controlled unevenness directly on the glass surface, the method eliminates complex coating applications and material selection processes while maintaining strong section attachment.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The glass slide serves itself by providing adhesion through its own modified surface structure rather than requiring external coating materials. The controlled unevenness created on the glass surface enables the slide to attach sections effectively without additional substances, simplifying the overall process.

Inventive Principle:
Principle #25Self-service

3Strength

If reactive ion etching is used to create surface unevenness, then adhesiveness is improved without additional materials, but the manufacturing process becomes more complex

Engineering Contradiction:
ImproveadhesivenessVSAvoidmanufacturing process
Core Design Contradiction:
StrengthVSEase of manufacture

Solution Approach 1:

The invention modifies the glass surface by controlling specific parameters of the reactive ion etching process (gas flow rate, power, time) to achieve the desired unevenness characteristics. By optimizing these parameters, the method creates the necessary surface structure for adhesion while managing the complexity of the manufacturing process.

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The technique effectively prevents section peeling and maintains high adhesiveness, allowing for reliable attachment of specimens without external coatings, while minimizing interference with microscopic observations and dyeing processes.

Implementation Method 1

etching at least a part of a region of a surface of a substrate with reactive ions

Methodology Applied
Scientific EffectReactive ion etching: Plasma

Implementation Method 2

By introducing a structure same as the unevenness introduced on the surface of the polystyrene particles shown in Non-Patent Document 1 to the surface of the microscope slide, the inventor attempted to improve adhesiveness of the sections

Methodology Applied
Scientific EffectReactive ion etching: Ablation

Data Source

PatentUS12032148B2Microscope slide, method for manufacturing microscope slide, observation method, and analysis method
Publication Date: 2024.07.09 HITACHI HIGH TECH CORP
  • US12032148B2 patent drawing
  • US12032148B2 patent drawing
  • US12032148B2 patent drawing

AI summary

It is not preferable to use a material other than materials that are used in the related art in order to prevent a section from peeling from a microscope slide. This is because, even if adhesiveness is improved, it is necessary to eliminate influence on processes such as dyeing. An object of the invention is to provide a technique for preventing a section from peeling off without applying an additional material. In the invention, the above-described problem is solved by etching at least a part of a region of a surface of a substrate with reactive ions.