Microscope Stage Insert With Multiple Calibration Targets

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Solution Overview

Problem

Current microscope calibration processes are labor-intensive and require manual exchange of calibration targets, leading to inefficiencies and potential errors, especially when dealing with complex applications that necessitate multiple calibrations and precise optical-digital combinations.

Innovation Solution

A stage insert for microscope systems featuring multiple calibration targets that allow for simultaneous or consecutive calibration of multiple parameters, eliminating the need for manual target changes and incorporating machine-readable identifiers for automated identification and positioning.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If multiple calibration targets are used on a single stage insert, then calibration efficiency and automation are improved, but device complexity increases

Engineering Contradiction:
Improvecalibration efficiencyVSAvoidstage insert structure
Core Design Contradiction:
ProductivityVSDevice complexity

Solution Approach 1:

Multiple calibration targets for different calibration purposes (alignment, distortion correction, spectral unmixing) are merged into a single stage insert, allowing all calibrations to be performed without manual target exchanges. This combines multiple functions into one integrated device, improving calibration efficiency while the modular design manages the complexity.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The stage insert is designed as a universal platform that can accommodate multiple types of calibration targets simultaneously, each serving different calibration needs. This multi-functional design allows a single device to perform alignment calibration, distortion correction, and spectral unmixing calibrations, reducing the need for multiple separate calibration devices.

Inventive Principle:
Principle #6Universality (Multi-functionality)

2Measurement precision

If manual calibration target exchange is required for different calibrations, then calibration accuracy can be maintained, but time consumption and operational complexity increase

Engineering Contradiction:
Improvecalibration accuracyVSAvoidcalibration time
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

Multiple calibration targets are pre-positioned on the stage insert in predetermined locations, allowing the system to automatically switch between them during calibration without manual intervention. This preliminary arrangement of all necessary targets eliminates time-consuming manual exchanges while maintaining calibration accuracy through pre-validated target positions.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The stage insert enables automated calibration by allowing the system to independently select and switch between different calibration targets based on the calibration type required. This self-service mechanism eliminates the need for manual target exchange, reducing both time consumption and operational complexity while preserving calibration accuracy.

Inventive Principle:
Principle #25Self-service

3Measurement precision

If multiple calibration parameters are calibrated simultaneously, then overall calibration accuracy is improved, but the complexity of calibration management increases

Engineering Contradiction:
Improveoverall calibration accuracyVSAvoidcalibration management
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The calibration process is segmented into distinct types (alignment, distortion correction, spectral unmixing), with each type having its dedicated calibration target on the stage insert. This segmentation allows the system to manage complex multi-parameter calibration by breaking it down into manageable, independently calibrated components, improving overall accuracy while controlling management complexity.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The stage insert acts as an intermediary that coordinates between different calibration targets and the microscope system. It manages the switching between targets and ensures proper positioning for each calibration type, simplifying the management of multiple calibration parameters by providing a centralized control interface.

Inventive Principle:
Principle #24Intermediary (Mediator)

Data Source

PatentUS20240095959A1Stage Insert, Microscope System, Apparatus, Method and Computer Program
Publication Date: 2024.03.21 LEICA MICROSYSTEMS CMS GMBH
  • US20240095959A1 patent drawing
  • US20240095959A1 patent drawing
  • US20240095959A1 patent drawing

AI summary

A stage insert is provided. The stage insert comprises a first region for accommodating a sample holder. Further, the stage insert comprises a second region comprising a first calibration target for calibrating a first parameter of the microscope system. The stage insert also comprises a third region comprising a second calibration target for calibrating a second parameter of the microscope system.