Ophthalmic Microscope Wavefront Adaptive Beam Control

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Solution Overview

Problem

Current microscopes used in eye surgery, particularly for interventions in the aqueous and vitreous humor, face challenges in achieving precise refraction measurements and compensating for individual eye defocusing and deformation, which affects the accuracy of OCT and treatment laser spot settings.

Innovation Solution

A microscope with integrated wavefront measuring devices and OCT systems that use a control unit to adjust the beam diameter and shape of OCT and treatment laser spots based on real-time refraction measurements, employing collimation optical units with axially displaceable lenses, liquid lenses, and adaptive mirrors to compensate for eye-induced defocusing and deformation.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If conventional OCT illumination is used without wavefront measurement, then the device complexity is lower, but the measurement precision of refraction and the accuracy of OCT spot settings deteriorate due to inability to compensate for individual eye defocusing and deformation

Engineering Contradiction:
Improverefraction measurement accuracyVSAvoidmicroscope system complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent combines the wavefront measuring device and OCT device into a single integrated microscope system, sharing common optical components such as the main objective, beam splitters, and collimation optical units. This merging approach enables high-precision refraction measurement and OCT spot setting accuracy while minimizing the increase in device complexity through component sharing and coordinated operation.

Inventive Principle:
Principle #5Merging (Combining)

2Manufacturing precision

If wavefront measurement and real-time compensation are implemented, then the OCT spot accuracy is improved, but the measurement time and processing time increase

Engineering Contradiction:
ImproveOCT spot setting accuracyVSAvoidmeasurement and processing time
Core Design Contradiction:
Manufacturing precisionVSLoss of time

Solution Approach 1:

The wavefront measurement is performed before the OCT imaging or treatment, allowing the refraction parameters to be determined in advance. The control unit then uses these pre-measured parameters to pre-adjust the collimation optical unit, ensuring that the OCT spot is accurately focused from the start, thereby eliminating the need for time-consuming real-time adjustments during imaging or treatment.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The control unit receives wavefront measurement data and automatically adjusts the collimation optical unit parameters based on this feedback. This closed-loop control system enables rapid computation and adjustment, minimizing the additional time required while maximizing OCT spot accuracy through adaptive optimization.

Inventive Principle:
Principle #23Feedback

3Manufacturing precision

If multiple optical components (collimation unit, adaptive mirrors) are added for beam control, then the beam diameter and shape control accuracy is improved, but the device complexity and ease of operation worsen

Engineering Contradiction:
Improvebeam diameter and shape control accuracyVSAvoidmicroscope operation simplicity
Core Design Contradiction:
Manufacturing precisionVSEase of operation

Solution Approach 1:

The control unit automatically controls the collimation optical unit and adaptive mirrors based on wavefront measurement data, eliminating the need for manual adjustment of these complex components. The system self-adjusts the beam diameter and shape parameters, providing high control accuracy while maintaining ease of operation through automated operation.

Inventive Principle:
Principle #25Self-service

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This configuration enables high-accuracy, real-time compensation for eye-specific aberrations, ensuring precise OCT imaging and targeted treatment laser delivery, enhancing the effectiveness of photocoagulation and photodisruption procedures.

Implementation Method 1

a wavefront measuring device for measuring the refraction of the eye to be examined

Methodology Applied
Scientific EffectWavefront measurement:

Implementation Method 2

The OCT device can comprise a collimation optical unit for collimating the OCT illumination radiation

Methodology Applied
Scientific EffectCollimation:

Implementation Method 3

the collimation optical unit can comprise an axially displaceable lens. For the purposes of setting the beam diameter of the OCT spot, the control unit can set the axial position of the lens

Methodology Applied
Scientific EffectLens focusing: Lens

Implementation Method 4

the collimation optical unit can comprise an adaptive mirror, the control unit actuating said adaptive mirror for the purposes of setting the beam diameter and/or the beam shape of the OCT spot

Methodology Applied
Scientific EffectAdaptive optics compensation:

Data Source

PatentUS10939816B2Microscope
Publication Date: 2021.03.09 CARL ZEISS MEDITEC AG
  • US10939816B2 patent drawing

AI summary

A microscope, comprising an observation beam path that renders an eye to be examined observable, a wavefront measuring device for measuring the refraction of the eye to be examined, an OCT device comprising an OCT illumination beam path, by means of which OCT illumination radiation can be focused as an OCT spot into the eye to be examined, and a control unit that is supplied with at least one measurement value of the wave front measuring device, is provided, wherein the control unit sets the beam diameter and/or the beam shape of the OCT spot on the basis of the at least one supplied measurement value.