Microscopic Hole Sensor Curved Orifice for Blood Cell Signal Accuracy
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Solution Overview
Problem
Conventional blood cell analyzers using the Coulter theory face issues with signal distortion due to anomalous paths and refluence, leading to inaccurate measurements and increased production costs from equipment needed to address jamming and signal quality issues.
Innovation Solution
A microscopic hole sensor assembly with a flow-guiding surface at the inlet and a downstream surface at the outlet, forming an effective orifice area that accelerates liquid flow and reduces refluence, improving signal quality and preventing jamming by maintaining a stable flow field and signal-to-noise ratio.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Device complexity
If a conventional microscopic hole sensor is used with perpendicular wall surfaces, then the structure is simple, but signal distortion occurs due to anomalous paths and refluence
Solution Approach 1:
The patent applies curvature by replacing the conventional perpendicular wall surfaces with curved surfaces. The inlet end surface is designed with a first curved surface that is not perpendicular to the orifice axis, and the outlet end surface has a second curved surface that is also not perpendicular. This curvature modification guides particle flow more smoothly through the orifice, eliminating anomalous paths and reducing refluence effects, thereby improving signal accuracy while maintaining structural simplicity.
2Productivity
If pressure is applied to drive liquid through the microscopic hole, then flow rate increases, but jamming occurs in the orifice path
Solution Approach 1:
The curved surfaces at the inlet and outlet ends of the orifice create a more gradual flow transition. The first curved surface at the inlet and the second curved surface at the outlet work together to smooth the flow field, preventing sudden changes in flow direction that cause jamming. This allows maintaining adequate flow rates while ensuring the orifice path remains clear of blocked particles.
Solution Approach 2:
The patent changes the geometric parameters of the orifice by modifying the angles of the inlet and outlet surfaces from perpendicular (90 degrees) to non-perpendicular curved surfaces. This parameter change optimizes the flow characteristics, allowing liquid to pass through the microscopic hole at controlled rates without causing jamming, thus improving both productivity and reliability.
3Measurement precision
If the orifice depth is increased to improve measurement, then signal quality improves, but production cost increases due to additional equipment for jam prevention
Solution Approach 1:
The curved surfaces modify the flow field within the orifice, improving signal quality by reducing anomalous paths and refluence effects. This approach achieves improved measurement precision without increasing the orifice depth or adding complex equipment for jam prevention, thereby maintaining ease of manufacture and reducing production costs.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The solution enhances the accuracy of blood cell counting by eliminating slow rise edges, M-shaped waves, and multi-peak signals, reducing production costs and preventing orifice path blockages, while maintaining a stable flow field and improved signal quality.
Implementation Method 1
an impedance detection method using Coulter theory is one of the main methods used by a blood analyzer for sorting and counting
Implementation Method 2
measurement of particles contained in a fluid according to different impedances resultant from different volumes of particles passing through a microscopic hole
Implementation Method 3
a flow-guiding surface at the inlet and a downstream surface at the outlet, forming an effective orifice area that accelerates liquid flow and reduces refluence
Data Source
AI summary
The present invention discloses a device for detecting blood cells and a microscopic hole sensor assembly thereof. The device includes a microscopic hole sensor assembly positioned between a front pool and a back pool. The microscopic hole sensor assembly further includes a microscopic hole plate with a microscopic hole positioned thereon for communicating the front pool and the back pool. The end surface of the inlet is a flow-guiding surface gradually narrowing from the front pool to the back pool. The end surface of the outlet is a downstream surface gradually distending and extending towards the back pool. A straight effective orifice area is formed connecting the ends of the flow-guiding surface and the downstream surface.