Microscopy Data Embedding for Automated Model Training

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Solution Overview

Problem

Current microscopy systems face challenges in achieving high-quality model training for processing microscope data due to manual intervention requirements for hyperparameter optimization, dataset division, and outlier identification, leading to potential biases and overfitting.

Innovation Solution

A computer-implemented method that embeds microscope data into a low-dimensional feature space to automatically determine training design specifications, including model architecture, dataset division, and hyperparameter optimization, allowing for automated identification of outliers and improved model training quality.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If manual division of dataset into training and validation data is performed by experts, then model quality is improved, but time consumption and operational complexity increase

Engineering Contradiction:
Improvemodel qualityVSAvoidtime consumption
Core Design Contradiction:
ReliabilityVSLoss of time

Solution Approach 1:

The system performs self-service by automatically analyzing the embedding structure to determine optimal training/validation data division. The embedding analysis module autonomously identifies data characteristics and recommends splitting strategies without requiring expert manual intervention, thus maintaining high model quality while reducing time consumption.

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The embedding serves as an intermediary that bridges raw microscope data and model training decisions. By transforming data into embedding space, the system enables automated analysis of data characteristics, which then informs optimal training/validation division strategies without direct expert intervention.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Ease of operation

If automated division of dataset is performed using simple criteria, then operational complexity is reduced, but model quality deteriorates due to bias and overfitting

Engineering Contradiction:
Improveoperational complexityVSAvoidmodel quality
Core Design Contradiction:
Ease of operationVSReliability

Solution Approach 1:

The embedding analysis acts as an intermediary that transforms simple automated division into intelligent data-driven division. By analyzing embedding structures, the system automatically identifies meaningful patterns and biases in the data, enabling automated division that maintains or improves model quality while reducing operational complexity.

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The system incorporates feedback loops where embedding analysis results inform and refine the automated data division process. The analysis of embedding characteristics provides feedback that adjusts division strategies to avoid biases and overfitting, ensuring model quality is maintained even with automated operations.

Inventive Principle:
Principle #23Feedback

3Reliability

If extensive manual activities are performed by experts to define model architecture and training parameters, then model quality is improved, but productivity decreases

Engineering Contradiction:
Improvemodel qualityVSAvoidtraining efficiency
Core Design Contradiction:
ReliabilityVSProductivity

Solution Approach 1:

The system performs self-service by automatically analyzing embeddings to determine optimal model architecture and training parameters. The embedding analysis module autonomously recommends configuration settings based on data characteristics, eliminating the need for extensive expert manual activities while maintaining high model quality and significantly improving training efficiency.

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The system performs preliminary action by conducting embedding analysis before model training to pre-determine optimal architecture and parameters. This advance analysis of data characteristics in embedding space enables automated configuration recommendations that would otherwise require extensive manual expert work, thus improving productivity without sacrificing model quality.

Inventive Principle:
Principle #10Preliminary action

4Ease of operation

If AutoML methods are used to automatically define model complexity and training parameters, then operational complexity is reduced, but time consumption increases due to cost-intensive and lengthy test training runs

Engineering Contradiction:
Improveoperational complexityVSAvoidtest training time
Core Design Contradiction:
Ease of operationVSLoss of time

Solution Approach 1:

The system performs preliminary action by conducting embedding analysis before model training to pre-determine optimal architecture and parameters. This advance analysis in embedding space provides informed recommendations that reduce or eliminate the need for extensive AutoML test training runs, thereby maintaining ease of operation while significantly reducing time consumption.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The system performs partial action by using embedding analysis to determine key architectural and parameter decisions, rather than conducting exhaustive AutoML searches. This partial automation approach focuses computational effort on the most critical decisions based on embedding characteristics, reducing overall time consumption while maintaining operational simplicity.

Inventive Principle:
Principle #16Partial or excessive action

Data Source

PatentUS20240070537A1Microscopy System and Method for Generating a Machine-Learned Model for Processing Microscope Data
Publication Date: 2024.02.29 CARL ZEISS MICROSCOPY GMBH
  • US20240070537A1 patent drawing
  • US20240070537A1 patent drawing
  • US20240070537A1 patent drawing

AI summary

A machine-learned model for processing microscope data is trained using a dataset containing microscope data. An embedding of the dataset in a feature space is calculated. The embedding is analyzed in order to determine training design specifications for a training of the model. The training is defined as a function of the training design specifications and subsequently implemented, whereby the model is configured to calculate a processing result from microscope data to be processed.