Microscopy Laser Calibration With Photodiode Feedback Stabilization

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Solution Overview

Problem

Existing laser systems in microscopy devices, such as blood cytometry devices, face challenges in maintaining a consistent and coherent laser output due to temperature changes and variations in photodiode properties, leading to inconsistent measurements and image quality.

Innovation Solution

A method and system for calibrating and stabilizing a laser by determining the slope of photodiode output change to input current change, selecting an operating photodiode output value, and adjusting the input current to maintain a stable photodiode output, using a controller and digital potentiometer to control the laser diode current, ensuring coherent light production.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Stability of the object's composition

If active heat regulation components are used to maintain laser output stability, then temperature stability is improved, but device complexity and size increase

Engineering Contradiction:
Improvelaser output stabilityVSAvoiddevice complexity
Core Design Contradiction:
Stability of the object's compositionVSDevice complexity

Solution Approach 1:

The patent replaces mechanical/thermal regulation systems with an electrical feedback control system. A photodiode monitors laser output intensity and feeds back to a controller that adjusts the laser diode current accordingly, eliminating the need for bulky active heat regulation components while maintaining output stability

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The patent implements a feedback control loop where a monitoring photodiode continuously measures the laser output intensity and feeds this information back to a controller. The controller compares the measured intensity with a target value and adjusts the input current to maintain stable output, resolving the contradiction between stability and complexity

Inventive Principle:
Principle #23Feedback

2Measurement precision

If photodiode monitoring is implemented to control laser intensity, then measurement precision is improved, but device complexity increases

Engineering Contradiction:
Improvelaser intensity measurement precisionVSAvoiddevice complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent uses the laser system's own output light to monitor its performance through a photodiode. The monitoring photodiode detects the actual laser intensity and feeds this information back for self-regulation, achieving precise measurement without adding complex external measurement equipment

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The patent makes the photodiode serve multiple functions: it acts as both a monitoring sensor for measurement precision and as part of the feedback control mechanism for stability regulation, reducing the need for separate components and minimizing overall device complexity

Inventive Principle:
Principle #6Universality (Multi-functionality)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach significantly improves the stability and consistency of the laser output, reducing costs and complexity, enabling accurate digital hologram generation in medical devices like blood cytometry without the need for bulky active heat regulation.

Implementation Method 1

a monitoring photodiode positioned to receive light from the illumination source

Methodology Applied
Scientific EffectPhotoelectric Effect: Photoelectric Effect

Implementation Method 2

the illumination source may be a laser diode having an input current threshold corresponding to a minimum input current at which the laser diode will produce coherent light

Methodology Applied
Scientific EffectLaser emission: Laser

Data Source

PatentUS20240332896A1Laser calibration and stabilization algorithm for microscopy device
Publication Date: 2024.10.03 HONEYWELL INTERNATIONAL INC
  • US20240332896A1 patent drawing
  • US20240332896A1 patent drawing
  • US20240332896A1 patent drawing

AI summary

A method, system, and computer program product for determining calibration parameters for controlling the intensity of a laser diode are provided. An example method may include determining a slope representing a relation of a change in a photodiode output value to an input current transmitted to the laser diode. In the example method, the photodiode output value is received from a monitoring photodiode positioned to receive light from the laser diode, wherein the photodiode output value corresponds to the intensity of light generated by the laser diode and received at the monitoring photodiode. The example method further includes selecting an operating photodiode output value based at least in part on the slope, wherein the operating photodiode output value corresponds to a target photodiode current at the monitoring photodiode during operation.