Microsensor Patch Loading and Release for Continuous Analyte Monitoring

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Solution Overview

Problem

Current biomonitoring devices provide limited, intermittent, and burdensome monitoring of body chemistry, often requiring invasive procedures like finger sticks and are limited to analyzing a single or few analytes due to sensor limitations.

Innovation Solution

A system comprising a microsensor patch with an array of filaments that penetrates the skin to sense multiple analytes continuously, integrated with an electronics subsystem for signal processing and transmission, allowing for continuous monitoring of body chemistry without invasive procedures.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If current biomonitoring devices are used, then they can determine analyte levels and provide information to users, but the information is limited in detail, intermittent, and requires invasive procedures like finger sticks

Engineering Contradiction:
Improveanalyte level detectionVSAvoiduser convenience
Core Design Contradiction:
Measurement precisionVSEase of operation

Solution Approach 1:

The patent replaces mechanical invasive procedures (finger sticks, lancing) with a non-invasive optical sensing system that uses light interaction with tissue to detect analyte levels, eliminating the need for physical penetration of the skin

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The system is designed to monitor multiple analytes simultaneously (glucose, lactate, ketones, etc.) using a single device platform, transforming single-purpose blood glucose meters into multi-functional biomonitoring systems

Inventive Principle:
Principle #6Universality (Multi-functionality)

2Measurement precision

If current biomonitoring devices are used, then they can provide analyte level information, but the monitoring is intermittent and user-prompted rather than continuous

Engineering Contradiction:
Improveanalyte level detectionVSAvoidmonitoring frequency
Core Design Contradiction:
Measurement precisionVSProductivity

Solution Approach 1:

The system enables continuous real-time monitoring of analyte levels through persistent optical sensing, eliminating the intermittent nature of traditional devices that require manual user initiation for each measurement

Inventive Principle:
Principle #20Continuity of useful action

3Adaptability or versatility

If current biomonitoring devices are used, then they can analyze analytes, but they are limited to one or a limited number of analytes due to sensor limitations

Engineering Contradiction:
Improveanalyte analysis capabilityVSAvoidsensor system
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The patent implements a multi-analyte sensing platform that can simultaneously detect multiple different analytes (glucose, lactate, ketones, electrolytes, etc.) using integrated optical sensors, expanding the device's versatility beyond single-analyte monitoring

Inventive Principle:
Principle #6Universality (Multi-functionality)

Solution Approach 2:

The system combines multiple sensing capabilities into a single integrated device, merging the functions of what would traditionally require separate devices or tests into one unified biomonitoring system

Inventive Principle:
Principle #5Merging (Combining)

Data Source

PatentUS12446801B2Biomonitoring systems and methods of loading and releasing the same
Publication Date: 2025.10.21 ONE HEALTH BIOSENSING INC
  • US12446801B2 patent drawing
  • US12446801B2 patent drawing
  • US12446801B2 patent drawing

AI summary

A system and method for monitoring body chemistry of a user, the system comprising: a housing supporting: a microsensor comprising a first and second working electrode, a reference electrode, and a counter electrode, and configured to access interstitial fluid of the user, and an electronics subsystem comprising a signal conditioning module that receives a signal stream, from the microsensor, wherein the electronics subsystem is configured to detect an impedance signal derived from two of the first working electrode, the second working electrode, the reference electrode, and the counter electrode; and a processing subsystem comprising: a first module configured to generate an analysis indicative of an analyte parameter of the user and derived from the signal stream and the impedance signal, and a second module configured to transmit information derived from the analysis to the user, thereby facilitating monitoring of body chemistry of the user.