Microtitre Plate with Variable Separation Matrix Volumes

The patent applies local quality by varying the separation matrix volume in different wells while keeping sample volume and concentration uniform. This creates local differences in the adsorption system (different matrix volumes) that enable diverse data collection without changing the sampling procedure, thus maintaining ease of operation while improving measurement precision for adsorption isotherm determination.

The patent segments the separation matrix volume across different wells, creating a series of discrete volume variations (e.g., 0.5 mL, 1.0 mL, 1.5 mL, 2.0 mL) that correspond to different data points on the adsorption isotherm. This segmentation approach enables precise measurement at multiple operating points while maintaining a simple overall device structure that can be implemented in standard microtitre plates.

The patent merges multiple adsorption measurements into a single experimental run by using different separation matrix volumes in parallel wells. Instead of performing separate experiments for each data point (which would consume more time and resources), all necessary measurements are combined in one plate, reducing both time loss and resource consumption while maintaining high measurement precision.

The patent changes the volume parameter of the separation matrix to create different operating conditions for adsorption studies. By varying this single parameter (matrix volume) while keeping other conditions constant, the system achieves high adaptability for studying adsorption equilibria at different points on the isotherm curve without requiring complex manufacturing precision, as volume variations can be achieved through simple filling procedures rather than precision manufacturing.