Microtome Blade Inspection Sensor with Imaging-Based Deterioration Detection

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Solution Overview

Problem

Existing microtomes rely on manual inspection of blades for irregularities, which is inefficient in detecting blade deterioration, leading to suboptimal cutting quality and potential damage to specimens.

Innovation Solution

A sensor device with an imaging unit and control unit is integrated into the microtome to capture and analyze blade images, determining blade state information through image comparison or machine learning, and automate blade replacement or adjustment.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If manual inspection of blades is used, then device complexity is low, but measurement precision and reliability of blade deterioration detection are insufficient

Engineering Contradiction:
Improveblade deterioration detection precisionVSAvoidsensor device complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent replaces manual mechanical inspection with an automated sensor device comprising an imaging unit and control unit. The imaging unit captures images of the blade edge, and the control unit processes these images to detect deterioration, substituting human visual inspection with electronic detection systems that provide higher precision and consistency.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The patent creates a digital copy (image) of the blade edge through the imaging unit. This image serves as a data representation that can be processed, stored, and compared without physical contact with the blade, enabling precise detection of deterioration patterns that are difficult to perceive during manual inspection.

Inventive Principle:
Principle #26Copying

2Productivity

If manual blade inspection is performed, then loss of time for inspection is high, but productivity is limited by inspection speed

Engineering Contradiction:
Improveblade inspection productivityVSAvoidtime for blade inspection
Core Design Contradiction:
ProductivityVSLoss of time

Solution Approach 1:

The sensor device enables continuous monitoring of blade condition during microtome operation. The imaging unit can capture images at regular intervals or when deterioration is detected, allowing uninterrupted inspection that maintains productivity while providing ongoing blade status information without requiring manual intervention.

Inventive Principle:
Principle #20Continuity of useful action

Solution Approach 2:

The system performs self-inspection through automated detection. The control unit processes images and determines blade state information autonomously, eliminating the need for manual inspection and allowing the microtome to continue operating without time loss for human evaluation of blade condition.

Inventive Principle:
Principle #25Self-service

3Reliability

If manual inspection methods are used, then ease of operation is high, but reliability of cut quality is compromised due to missed irregularities

Engineering Contradiction:
Improvecut quality reliabilityVSAvoidblade inspection operation ease
Core Design Contradiction:
ReliabilityVSEase of operation

Solution Approach 1:

The control unit provides feedback about blade condition by processing images and determining blade state information. This feedback mechanism alerts users to blade deterioration before it affects cut quality, maintaining high reliability of specimen preparation while requiring minimal user action beyond monitoring the system's assessments.

Inventive Principle:
Principle #23Feedback

Solution Approach 2:

The patent replaces subjective manual evaluation with objective electronic detection. The imaging unit and control unit provide consistent, repeatable measurements of blade edge conditions, eliminating the variability in human perception and ensuring reliable detection of irregularities that compromise cut quality.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

4Productivity

If blade replacement is done manually, then device complexity is low, but productivity is reduced due to frequent manual interventions

Engineering Contradiction:
Improvemicrotome productivityVSAvoidautomated blade replacement system complexity
Core Design Contradiction:
ProductivityVSDevice complexity

Solution Approach 1:

The control unit continuously monitors blade condition through image processing and provides feedback that triggers automated blade replacement when deterioration thresholds are exceeded. This feedback-driven automation maintains high productivity by eliminating manual inspection and replacement intervals, while the system complexity is managed through integrated control logic.

Inventive Principle:
Principle #23Feedback

Solution Approach 2:

The microtome system performs self-maintenance through automated blade replacement. When the control unit detects blade deterioration, it automatically initiates the blade replacement process without human intervention, allowing the system to maintain optimal performance continuously and improving productivity despite the added automation complexity.

Inventive Principle:
Principle #25Self-service

Data Source

PatentEP4600630A1Sensor device and method for inspecting a blade of a microtome and microtome
Publication Date: 2025.08.13 LEICA BIOSYSTEMS NUSSLOCH GMBH
  • EP4600630A1 patent drawingFigure 1
  • EP4600630A1 patent drawingFigure 2
  • EP4600630A1 patent drawing

AI summary

A sensor device for inspecting a blade (108) of a microtome (100) comprises an imaging device arrangeable on the microtome (100) and configured to capture at least one image of an edge of the blade (108) and to generate image data corresponding to said image. The sensor device further comprises a control unit (122) configured to receive and process the image data and to determine a blade state information based on the image data, the blade state information corresponding to a state of deterioration of the blade (108).