Microwave Skin Hydration Sensing With Calibration Compensation
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Solution Overview
Problem
Existing non-invasive blood glucose measurement systems fail to provide real-time, accurate readings due to the difficulty in directly measuring glucose levels in the bloodstream, relying instead on interstitial fluid measurements with significant time lags and inaccuracies.
Innovation Solution
A non-invasive system that measures blood glucose levels by transmitting microwave energy to subcutaneous blood vessels, using a tailored RF mask to focus energy on a specific target area, and calculating glucose levels based on the difference between instantaneous and calibrated power readings, with additional sensors for compensation.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Ease of operation
If non-invasive optical methods are used to measure blood glucose levels, then the measurement can be performed without breaking the skin, but the measurements are inaccurate and fail to provide real-time readings
Solution Approach 1:
The patent replaces optical measurement methods with microwave radiation methods. Instead of using light to detect glucose levels, the system uses microwave energy transmitted through the skin to subcutaneous blood vessels, where the glucose concentration affects the absorption characteristics of the blood, enabling accurate non-invasive measurement.
Solution Approach 2:
The patent changes the physical parameter used for measurement from optical properties to microwave absorption properties. By measuring the absorption of microwave energy at specific frequencies by blood in subcutaneous vessels, the system can determine glucose levels accurately without the limitations of optical methods.
2Productivity
If interstitial fluid glucose levels are measured instead of direct blood glucose levels, then continuous monitoring is possible, but a substantial time lag of about 20 minutes occurs
Solution Approach 1:
The patent extracts the measurement target from interstitial fluid to direct blood in subcutaneous vessels. By positioning the microwave transmission path to target subcutaneous blood vessels specifically, the system measures actual blood glucose levels rather than interstitial fluid glucose, eliminating the time lag while maintaining continuous monitoring capability.
3Measurement precision
If microwave energy is transmitted to subcutaneous blood vessels for direct blood glucose measurement, then real-time accurate readings are obtained, but the device complexity increases
Solution Approach 1:
The patent implements preliminary calibration procedures where the system is calibrated against known blood glucose values before actual measurement. This pre-calibration step establishes the relationship between microwave absorption characteristics and glucose concentrations, simplifying subsequent measurements while maintaining high accuracy.
Solution Approach 2:
The system incorporates feedback mechanisms where calibration data and measurement results are used to adjust and refine the measurement algorithm. This feedback loop allows the complex microwave-based system to adapt to individual variations and maintain measurement accuracy without requiring overly complex hardware.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
Provides real-time, accurate blood glucose measurements without time lag, directly from the bloodstream, using a compact wearable device that compensates for individual variations.
Implementation Method 1
transmitting microwave energy to subcutaneous blood vessels... measures the amount of power/energy delivered through the antenna
Data Source
AI summary
A hydration level tracking system and method measures microwave energy accepted by skin in a desired target area of a user or patient in order to determine, in real time and in vivo, representative hydration levels. A measurement unit comprises a transmitter operatively connected to an antenna to deliver energy towards appropriate layer. The measurement unit determines an accepted energy power value of the skin associated with the desired target area. This measurement energy power value is compared with a calibration value, and the difference is used to determine a representative hydration level value. The determined hydration value may further be acclimatized using additional sensed values compensating for biological and ambient factors relevant to the patient. The final determined hydration level value can be displayed for reading and/or transmitted and stored for recording for further reference.


