Mid-Frequency AC Tissue Transducer for Deeper Tumor Field Penetration
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Solution Overview
Problem
Current Tumor-Treating Therapy (TTF) is costly, limited in its ability to reach cancerous growths, and difficult to implement, necessitating a more effective and affordable method to control cancer cell growth.
Innovation Solution
The application of mid-level frequency AC current electromagnetic signals, ranging from 50 kHz to 300 kHz, with modulating amplitude, frequency, and random pulse duration, is used to inhibit the growth of proliferating cells by improving penetration and reducing attenuation, utilizing a transducer with a magnetically conductive material and a conduction ring energized by an electrical signal.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If current TTF therapy is used to treat cancer cells, then cancer cell growth is inhibited, but the treatment is costly and has limited penetration ability
Solution Approach 1:
The patent changes the frequency parameter of the AC current from conventional TTF ranges to mid-level frequencies (50-300 kHz), which fundamentally alters the penetration and cytotoxicity characteristics of the electromagnetic signals, achieving both deeper tissue penetration and enhanced cancer cell inhibition
Solution Approach 2:
The patent employs dynamic modulation of the AC current parameters including amplitude modulation, frequency modulation, and random pulse duration to optimize the electromagnetic signal delivery, making the treatment more adaptable and effective while potentially reducing overall treatment cost
2Length of stationary object
If higher frequency AC current is used to improve penetration, then penetration depth increases, but signal attenuation increases
Solution Approach 1:
The patent identifies and applies the optimal frequency range (50-300 kHz) where penetration depth is maximized while attenuation is minimized, representing a critical parameter optimization that resolves the trade-off between penetration and energy loss
Solution Approach 2:
The use of alternating current at specific periodic frequencies creates resonant effects and optimizes tissue penetration while managing energy dissipation, allowing deeper penetration without proportional increases in attenuation
3Productivity
If mid-level frequency AC current is applied to proliferating cells, then cytotoxicity to cancer cells increases, but the mechanism of action must be precisely controlled
Solution Approach 1:
The patent implements dynamic control mechanisms including amplitude modulation, frequency modulation, and random pulse duration to precisely regulate the electromagnetic signal delivery, optimizing cytotoxicity while managing the inherent complexity of the modulation system
Solution Approach 2:
The system incorporates feedback mechanisms to monitor and adjust the AC current parameters in real-time, ensuring optimal cytotoxicity is achieved while automatically managing the complexity of signal control through adaptive regulation
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
This method provides a lower-cost alternative to existing TTF treatments, achieving significantly greater cytotoxicity to cancer cells with improved transmission of AC current electromagnetic signals, resulting in enhanced treatment efficacy.
Implementation Method 1
applying mid-level frequency AC current electromagnetic signals to the living tissue with a transducer comprising a magnetically conductive material passing through a conduction ring energized by an electrical signal to create the mid-level frequency AC current electromagnetic signals within the living tissue
Implementation Method 2
a transducer comprising a magnetically conductive material passing through a conduction ring energized by an electrical signal
Data Source
AI summary
The present invention provides a method of inhibiting the growth of proliferating cells or viruses in living tissue, the method comprising: applying mid-level frequency AC current electromagnetic signals to the living tissue with a transducer comprising a magnetically conductive material passing through a conduction ring energized by an electrical signal to create the mid-level frequency AC current electromagnetic signals within the living tissue; wherein the mid-level frequency AC current electromagnetic signals have a frequency in the range of about 50 kHz to about 300 kHz and are produced with an AC voltage generator; and circulating fluid in the living tissue provide a secondary coil for the transmission of the mid-level frequency AC current electromagnetic signals.