Mineral-Enzyme Complex for Enamel Strengthening and Cleaning

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Solution Overview

Problem

Existing oral cavity hygiene agents using mineral and enzyme complexes lack comprehensive protective properties, such as inadequate cleaning, weak enamel strengthening, insufficient whitening, and limited anti-inflammatory and blood-stopping actions.

Innovation Solution

A mineral-enzyme complex comprising calcium hydroxyapatite and tannase, with grapeseed extract, is used in compositions like toothpaste, rinses, and chewing gum, providing enhanced cleaning, whitening, desensitizing, anti-inflammatory, and blood-stopping effects while maintaining enamel strengthening.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Strength

If mineral complexes (calcium hydroxyapatite) are used in oral hygiene compositions, then tooth mineralization and enamel resistance are improved, but cleaning properties and whitening effects are insufficient

Engineering Contradiction:
Improveenamel resistanceVSAvoidcleaning properties
Core Design Contradiction:
StrengthVSProductivity

Solution Approach 1:

The patent combines mineral complexes (calcium hydroxyapatite) with enzyme complexes (papain, lidase, ribonuclease, lysozyme) in a single oral hygiene composition. This merging allows the composition to simultaneously provide enamel strengthening through mineralization and effective cleaning through enzymatic action on plaque and organic deposits, resolving the contradiction between strength improvement and cleaning productivity.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The invention creates a composite functional system by integrating inorganic mineral components (calcium hydroxyapatite for remineralization) with organic enzymatic components (proteases, lipases, nucleases for cleaning). This composite approach enables the single composition to deliver multiple functions: both the enamel-strengthening property from minerals and the high cleaning productivity from enzymes, eliminating the need to choose between them.

Inventive Principle:
Principle #40Composite materials

2Productivity

If enzyme complexes are used in oral hygiene compositions, then cleaning and anti-inflammatory action are improved, but enamel strengthening and mineralization effects are insufficient

Engineering Contradiction:
Improvecleaning actionVSAvoidenamel strengthening
Core Design Contradiction:
ProductivityVSStrength

Solution Approach 1:

The patent merges enzyme complexes (providing cleaning and anti-inflammatory actions) with mineral complexes (calcium hydroxyapatite providing enamel strengthening). The enzymatic components papain, lidase, ribonuclease and lysozyme deliver high cleaning productivity and anti-inflammatory effects, while the calcium hydroxyapatite simultaneously provides the necessary enamel strengthening and mineralization, resolving the contradiction between cleaning productivity and enamel strength.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The invention forms a composite system where organic enzymatic substances work synergistically with inorganic mineral substances. The enzyme complex handles organic debris and inflammation while the mineral complex handles enamel reinforcement, creating a unified composition that achieves both high cleaning action and effective enamel strengthening without compromise.

Inventive Principle:
Principle #40Composite materials

3Productivity

If individual enzymes are used in oral hygiene compositions, then specific functions (cleaning, whitening, anti-inflammatory) are improved, but comprehensive protective properties are insufficient

Engineering Contradiction:
Improvespecific function effectivenessVSAvoidcomprehensive protective properties
Core Design Contradiction:
ProductivityVSAdaptability or versatility

Solution Approach 1:

The patent creates a multi-functional composition by combining four different enzymes (papain for protein breakdown, lidase for lipid breakdown, ribonuclease for RNA breakdown, and lysozyme for bacterial cell wall breakdown) with calcium hydroxyapatite. This universal enzyme-mineral complex simultaneously provides cleaning, whitening, anti-inflammatory, and enamel-strengthening functions, achieving comprehensive protective properties that individual enzymes cannot provide alone.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Solution Approach 2:

The invention merges multiple enzymatic functions into a single integrated complex system. By combining proteases, lipases, nucleases, and antibacterial enzymes with mineral components, the composition achieves versatility across multiple oral health functions: cleaning plaque, removing stains, reducing inflammation, and strengthening enamel, thereby achieving comprehensive protection that individual enzymes lack.

Inventive Principle:
Principle #5Merging (Combining)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The complex achieves significant improvements in cleaning, whitening, desensitizing, anti-inflammatory, and blood-stopping effectiveness, along with enamel strengthening, as demonstrated by clinical trial results.

Implementation Method 1

tannase, when used in oral cavity hygiene agents, helps remove color blemishes since it hydrolizes tannins contained in tea and coffee that cause tooth discoloration

Methodology Applied
Scientific EffectHydrolization: Hydrolysis

Implementation Method 2

Calcium hydroxyapatite, in turn, fills dental tubules from the entrance aperture to the depth of the tubule, tightly sealing the entrance itself

Methodology Applied
Scientific EffectAdsorption: Adsorption

Implementation Method 3

sodium fluoride preventing the adsorption of organic substances and microorganisms on the surface of the enamel

Methodology Applied
Scientific EffectAdsorption prevention: Adsorption

Data Source

PatentEP2902008B1Mineral-enzyme complex for fortifying and whitening tooth enamel, oral hygiene composition and toothpaste
Publication Date: 2019.02.13 OBSHCHESTVO S OGRANICHENNOJ OTVETSTVENNOSTYU SPLAT GLOBAL

AI summary

The invention relates to cosmetology, and more particularly to a mineral-enzyme complex for fortifying and whitening tooth enamel, as well as to oral hygiene compositions containing the aforesaid complex and particularly to toothpastes and other compositions. The mineral-enzyme complex for fortifying and whitening tooth enamel is characterized in that it contains hydroxyapatite and tannase in the following component ratio: 0.2-10 parts per weight tannase to 100 parts per weight hydroxyapatite. The complex may additionally contain grape seed extract. Also disclosed are various oral hygiene compositions containing the claimed mineral-enzyme complex. The invention makes it possible to improve the consumer qualities of the complex and of oral hygiene compositions containing the claimed mineral-enzyme complex, namely: cleaning ability, whitening properties, reduced inflammation and bleeding of the gums, and an enhanced desensitizing effect together with a remineralizing effect on dental tissue.