Miniature Intelligent Urine Sensing System With Multi-Channel Electrochemical Detection

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Solution Overview

Problem

Existing urine detection devices are bulky, limited in use due to single-type biosensor or enzyme-based structures, and require professional operation, making them inconvenient for home use and delayed treatment, especially for patients who need continuous monitoring.

Innovation Solution

A miniature and intelligent urine sensing system with a multi-channel urine sensor test piece and wireless transceiving circuit, integrating micropumps, micromixers, and electrolytic chambers for electrochemical sensing, capable of detecting various substances and transmitting data to the cloud for analysis, using a System on a Chip (SoC) for miniaturization and IoT connectivity.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If enzyme based sensors with optical detection are used, then detection capability is achieved, but waiting time for detection results becomes long

Engineering Contradiction:
Improvedetection capabilityVSAvoidwaiting time
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The patent replaces enzyme-based optical detection with non-enzyme-based electrochemical sensors that provide rapid electrical signal output, eliminating the long waiting time associated with optical detection methods while maintaining detection capability

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The patent changes the detection parameter from optical signal to electrical signal by using non-enzyme-based sensors, which enables faster response time and real-time monitoring without the delays inherent in enzyme-based optical systems

Inventive Principle:
Principle #35Parameter changes

2Device complexity

If single type biosensor or enzyme based structure is used, then device complexity is reduced, but adaptability for detecting various substances deteriorates

Engineering Contradiction:
Improvestructure simplicityVSAvoiddetection range
Core Design Contradiction:
Device complexityVSAdaptability or versatility

Solution Approach 1:

The patent designs a multi-channel sensor array where each channel can detect different substances (glucose, cholesterol, uric acid, etc.) using non-enzyme-based sensing elements, enabling a single device to perform multiple detection functions without requiring different sensor types

Inventive Principle:
Principle #6Universality (Multi-functionality)

Solution Approach 2:

The patent divides the sensing system into multiple independent channels, each equipped with specific non-enzyme-based sensors for different analytes, allowing parallel detection of various substances while maintaining overall system simplicity

Inventive Principle:
Principle #1Segmentation

3Adaptability or versatility

If impedance based measurement is used for enzyme based test piece, then compatibility is achieved, but device complexity increases

Engineering Contradiction:
ImprovecompatibilityVSAvoiddetection circuit complexity
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The patent replaces impedance-based measurement circuits with simplified voltage or current measurement circuits that are inherently simpler and more straightforward, achieving compatibility with non-enzyme-based sensors without requiring complex detection circuitry

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

4Ease of operation

If home self-detection device with handheld equipment is used, then ease of operation improves, but volume of device increases

Engineering Contradiction:
Improveuser convenienceVSAvoiddevice volume
Core Design Contradiction:
Ease of operationVSVolume of moving object

Solution Approach 1:

The patent merges the sensor test piece and detection device into a single integrated unit, eliminating the need for separate handheld equipment and reducing overall device volume while maintaining ease of operation through simple insertion and automatic detection

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The patent embeds the detection circuitry and processing units within the sensor test piece itself, creating a compact nested structure where smaller functional components are integrated into the larger test piece architecture, minimizing external device requirements

Inventive Principle:
Principle #7Nested doll (Nesting)

5Adaptability or versatility

If urine detection test piece is carried for measurement, then detection flexibility improves, but ease of operation deteriorates for bedridden patients

Engineering Contradiction:
Improvedetection flexibilityVSAvoidoperational convenience
Core Design Contradiction:
Adaptability or versatilityVSEase of operation

Solution Approach 1:

The patent designs the sensor test piece to be self-contained and automatically perform detection without requiring user manipulation or carrying, with features like automatic sample uptake and integrated processing that eliminate the need for active user involvement in the detection process

Inventive Principle:
Principle #25Self-service

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enables portable, user-friendly urine detection anywhere, providing immediate analysis and risk assessment for heart and kidney diseases through AI algorithms, facilitating early screening and prevention.

Implementation Method 1

electrochemical sensing when being activated

Methodology Applied
Scientific EffectElectrochemical sensing: Electrochemiluminescence

Implementation Method 2

arranged with multiple micropumps, micromixers

Methodology Applied
Scientific EffectMicropump: Microfluidic Pump

Implementation Method 3

electrochemical sensing when being activated

Methodology Applied
Scientific EffectElectrochemical sensing: Electrochemiluminescence

Implementation Method 4

electrolytic chambers for accommodating electrolyte solution therein

Methodology Applied
Scientific EffectElectrolyte: Electrolyte

Implementation Method 5

wireless transceiving circuit, capable of detecting various substances and transmitting data to the cloud

Methodology Applied
Scientific EffectWireless transmission: Electromagnetic Induction

Data Source

PatentUS11478176B2Miniature and intelligent urine sensing system
Publication Date: 2022.10.25 NAT CHENG KUNG UNIV
  • US11478176B2 patent drawing
  • US11478176B2 patent drawing
  • US11478176B2 patent drawing

AI summary

In a microrunner structure, there are provided with components for a cleaning procedure required to conduct electrochemical sensing when a biosensor is activated for sensing; and a urine signal detection device that is a SoC (System on a Chip), which has a wireless transceiving circuit for receiving a urine measurement method and channel information transmitted from an intelligent device, and in turn, outputting a stimulus signal to trigger a biosensor or a non-biosensor in a multi-channel structure to conduct urine sense processing for a sensing area, as well as transmitting detection processing for a concentration of urine substances from the electrochemical sensing to the intelligent device through the wireless transceiving circuit to assess a risk index between a heart disease or diabetes and a kidney disease.