Miracle Fruit Extract Topical Formulations for Skin and Joint Conditions
Find Innovative SolutionsGenerate Solutions
Solution Overview
Problem
Existing topical compositions fail to effectively harness the unique properties of miracle fruit (Synsepalum dulcificum) extracts for anti-inflammatory, antimicrobial, and regenerative benefits, particularly in treating skin, hair, nail, and joint conditions.
Innovation Solution
A composition comprising extracts from the seed, skin, or pulp of miracle fruit, including miracle fruit seed oil (MFSO) and other extracts, which contain specific fatty acids, triterpene alcohols, and phytosterols, is formulated for topical administration using various delivery systems.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If miracle fruit extracts are used in topical compositions, then anti-inflammatory and antimicrobial effects are achieved, but the compositions fail to effectively harness the unique properties of the extracts
Solution Approach 1:
The patent optimizes the concentration parameters of miracle fruit extracts and their active components (miraculin, synsepalum dulcificum) in the topical composition to enhance anti-inflammatory and antimicrobial effectiveness. By adjusting extract concentration, solvent type, and formulation parameters, the composition achieves reliable therapeutic effects while maintaining formulation feasibility.
2Reliability
If miracle fruit seed oil is used for its regenerative properties, then skin and hair health is improved, but the composition lacks adequate delivery systems for effective topical administration
Solution Approach 1:
The patent incorporates appropriate carriers, emulsifiers, and penetration enhancers as intermediary substances to facilitate the delivery of miracle fruit seed oil and extracts through the skin and hair shaft. These delivery system components act as mediators that enhance penetration and retention of the active ingredients while maintaining formulation stability and ease of application.
3Reliability
If the composition is formulated with multiple extracts from seed, skin, and pulp, then comprehensive therapeutic benefits are achieved, but the manufacturing process becomes more complex
Solution Approach 1:
The patent segments the miracle fruit into distinct components (seed, skin, pulp) and extracts each separately to preserve their unique therapeutic properties. This segmentation allows for optimized extraction conditions for each part and facilitates standardized formulation processes, thereby simplifying manufacturing while achieving comprehensive therapeutic benefits from all fruit components.
4Adaptability or versatility
If the composition acts as both a lubricant and spermicide, then multiple functions are achieved, but the formulation stability becomes more difficult to maintain
Solution Approach 1:
The patent formulates the miracle fruit composition to simultaneously exhibit lubricant and spermicide properties by incorporating appropriate concentrations of miracle fruit extracts, oils, and auxiliary ingredients. The formulation achieves multi-functionality while maintaining stability through careful selection of compatible ingredients, pH control, and optimized concentration ranges that prevent precipitation, separation, or degradation of active components.
Data Source
AI summary
Compositions and methods of treatment are disclosed using compositions of extracts from the fruit of the Synsepalum dulcificum tree, which when applied topically in mammals, can provide benefit for dermatological and joint conditions. The extracts also contain anti-inflammatory, antimicrobial and spermicidal activity in vitro.