Mitochondrial Protection Composition Using Haematococcus pluvialis

Resolve Bottlenecks,
Find Innovative Solutions
Generate Solutions

Solution Overview

Problem

Current methods fail to effectively address mitochondrial dysfunction, which is associated with aging and various diseases, by not adequately improving oxidative stress levels and delaying mitochondrion-related aging.

Innovation Solution

A composition comprising Haematococcus pluvialis, Lycium ruthenicum, Cordyceps militaris, and nicotinamide in specific mass ratios, extracted using ethanol and water, is used to prepare a product that improves mitochondrial function by enhancing SOD enzyme activity, NAMPT enzyme activity, and protein expression of the respiratory chain complex.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If single constituents are used to protect mitochondrial function, then the effect is limited, but the composition complexity increases when multiple ingredients are combined

Engineering Contradiction:
Improvemitochondrial protection effectVSAvoidcomposition complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent combines four different constituents (Haematococcus pluvialis, Lycium ruthenicum, Cordyceps militaris, and nicotinamide) into a single composition to achieve synergistic effects. Each ingredient targets different aspects of mitochondrial function, and their combination produces a protective effect greater than the sum of individual components, resolving the contradiction between effect strength and composition simplicity.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The invention creates a composite formulation where multiple natural extracts and supplements work together. The specific mass ratios (Haematococcus pluvialis: Lycium ruthenicum: Cordyceps militaris: nicotinamide = 100-450: 200-800: 50-150: 0.1-10) are optimized to achieve synergistic mitochondrial protection while maintaining manageable composition complexity.

Inventive Principle:
Principle #40Composite materials

2Object-affected harmful factors

If mitochondrial dysfunction is not addressed, then oxidative stress levels remain high and aging accelerates, but current methods fail to effectively improve these conditions

Engineering Contradiction:
Improveoxidative stress levelVSAvoideffectiveness of current methods
Core Design Contradiction:
Object-affected harmful factorsVSReliability

Solution Approach 1:

The composition converts the harmful oxidative stress into a beneficial outcome by using antioxidants from natural sources to neutralize free radicals. The constituents transform the damaging oxidative environment into a protected state, effectively addressing mitochondrial dysfunction and reducing oxidative stress levels while delaying aging.

Inventive Principle:
Principle #22Blessing in disguise (Convert harm into benefit)

Solution Approach 2:

The invention changes key parameters including SOD enzyme activity, NAMPT enzyme activity, and protein expression of respiratory chain complexes. By optimizing these biochemical parameters through the composition, the patent effectively improves mitochondrial function and reduces oxidative stress, overcoming the limitations of current methods.

Inventive Principle:
Principle #35Parameter changes

Data Source

PatentUS11779625B2Composition and application thereof in preparing product for protecting mitochondria
Publication Date: 2023.10.10 INFINITUS (CHINA) CO LTD
  • US11779625B2 patent drawing
  • US11779625B2 patent drawing
  • US11779625B2 patent drawing

AI summary

The invention relates to the field of health food technologies, and particularly to a composition and an application thereof in preparing a product for protecting mitochondria. The invention provides a composition, the raw materials of which include Haematococcus pluvialis, Lycium ruthenicum, Cordyceps militaris and nicotinamide. The composition has the effects of improving an oxidative stress level under a mitochondrial dysfunction and delaying mitochondrion-related aging. Compared with a single constituent, constituents in the composition cooperate with each other to produce a synergistic effect, which significantly improves an effect of protecting a mitochondrial function.