Mitral Valve Sealing Assembly for Fast Leaflet Capture

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Solution Overview

Problem

Existing treatments for mitral regurgitation, such as surgical stitching and catheter-delivered clips, are inadequate as they either require extensive operation time or create stress on patient leaflets, and there is a need for improved devices and methods to treat this condition.

Innovation Solution

An implantable prosthetic device with a coaption element and anchoring means, featuring moveable paddles and barbed clasps, is designed to be deployed via a delivery sheath, allowing for secure capture and sealing of native heart valve leaflets, reducing regurgitation by anchoring between the leaflets.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If surgical stitching is used to treat mitral regurgitation, then the valve can be repaired, but the operation time is extensive

Engineering Contradiction:
Improvevalve repair effectivenessVSAvoidoperation time
Core Design Contradiction:
ReliabilityVSLoss of time

Solution Approach 1:

The invention extracts the complex surgical stitching process by providing a pre-formed coaption element that can be delivered via catheter. The coaption element is a self-contained structure with integrated anchoring features (paddles and clasps) that eliminates the need for time-consuming surgical stitching while maintaining valve repair effectiveness

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The coaption element serves as an intermediary device that bridges the gap between surgical and percutaneous approaches. It provides surgical-level repair capability through a percutaneous delivery system, acting as a mediator that combines the advantages of both approaches while avoiding their disadvantages

Inventive Principle:
Principle #24Intermediary (Mediator)

2Ease of operation

If catheter-delivered clips are used to treat mitral regurgitation, then the procedure is less invasive, but stress is created on patient leaflets

Engineering Contradiction:
Improveminimally invasive procedureVSAvoidstress on leaflets
Core Design Contradiction:
Ease of operationVSObject-affected harmful factors

Solution Approach 1:

The coaption element is segmented into multiple functional components: the coaption portion for sealing, multiple paddles for distributed anchoring, and multiple clasps for secure leaflet capture. This segmentation distributes the mechanical load across multiple attachment points rather than concentrating stress at a single clip location, reducing harm to the leaflets while maintaining procedural minimality

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The paddles are designed to be moveable from a closed position to an open position, allowing the device to adapt dynamically to the valve anatomy during deployment. This dynamic capability enables optimal positioning and load distribution, reducing stress on the leaflets while maintaining secure anchoring

Inventive Principle:
Principle #15Dynamics

3Reliability

If multiple clips are used on the commissures, then leaflet capture is improved, but operation time increases

Engineering Contradiction:
Improveleaflet captureVSAvoidoperation time
Core Design Contradiction:
ReliabilityVSLoss of time

Solution Approach 1:

The invention merges multiple leaflet capture functions into a single integrated coaption element with multiple paddles and clasps. This unified structure achieves reliable leaflet capture at multiple locations simultaneously through one deployment action, eliminating the need for sequential clip placement while maintaining comprehensive leaflet engagement

Inventive Principle:
Principle #5Merging (Combining)

Data Source

PatentEP4509066B1Heart valve sealing devices and delivery devices therefor
Publication Date: 2025.12.24 EDWARDS LIFESCIENCES CORP
  • EP4509066B1 patent drawingFigure 1~2
  • EP4509066B1 patent drawingFigure 3~4
  • EP4509066B1 patent drawingFigure 5~6

AI summary

An implantable prosthetic device includes a coaption portion, paddles, and clasps. The paddles are moveable from a closed position to an open position. The clasps are also moveable from an open position to a closed position. The implantable prosthetic device can be used to repair a naitive valve, such as a native mitral valve.