Mitral Valve Prosthesis Ring Layout to Prevent LVOT Obstruction
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Solution Overview
Problem
Current mitral valve bioprosthesis risk left ventricular outflow tract obstruction due to abnormal displacement of the native anterior leaflet, impairing left ventricular function and heart pump capability, as complete removal or modification of the anterior leaflet is necessary for valve replacement.
Innovation Solution
A mitral valve prosthesis device comprising a stent frame assembly with a peripheral ring and valve leaflets, designed to fit over the native mitral valve annulus, limiting protrusion into the ventricular chamber and reducing the effect on ventricular outflow, allowing full retention of the native leaflet without obstruction.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If the native anterior mitral leaflet is fully retained during bioprosthesis implantation, then left ventricular function and heart pump capability are preserved, but left ventricular outflow tract obstruction occurs due to abnormal displacement of the native leaflet by the bioprosthesis
Solution Approach 1:
A peripheral ring is introduced as an intermediary component between the bioprosthesis and the native mitral valve annulus. This ring positions the bioprosthesis to limit protrusion into the ventricular chamber, thereby preventing abnormal displacement of the native anterior leaflet while preserving its function. The peripheral ring acts as a mediator that resolves the conflict between retaining the native leaflet and preventing outflow tract obstruction.
Solution Approach 2:
The design modifies the spatial parameters of the bioprosthesis by controlling its protrusion depth into the ventricular chamber. By adjusting the position of the bioprosthesis relative to the mitral valve annulus through the peripheral ring, the system changes the geometric parameters to prevent leaflet displacement while maintaining valve function.
2Object-affected harmful factors
If the anterior mitral leaflet is completely removed or substantially modified during valve replacement, then left ventricular outflow tract obstruction is prevented, but left ventricular function and heart pump capability are substantially impaired
Solution Approach 1:
The peripheral ring serves as a positioning intermediary that enables the bioprosthesis to function without requiring removal or modification of the native anterior leaflet. By mediating the spatial relationship between the prosthesis and native valve, it prevents outflow tract obstruction while preserving the leaflet's contribution to left ventricular function.
3Reliability
If the bioprosthesis protrudes into the ventricular chamber to ensure proper valve function, then valve performance is improved, but the native leaflet is displaced below the aortic valve causing outflow tract obstruction
Solution Approach 1:
The system optimizes the positional parameters of the bioprosthesis by using the peripheral ring to limit protrusion depth. This parameter control ensures the bioprosthesis maintains adequate valve function while preventing the native leaflet from being displaced below the aortic valve level, thereby avoiding outflow tract obstruction.
Data Source
AI summary
Provided are devices and methods for augmenting mitral valve function. A cardiac valve prosthesis device comprises a stent frame assembly having an atrial portion and a ventricular portion, a peripheral ring attached to the stent frame assembly, which divides the stent frame assembly into the atrial and ventricular portions, and a plurality of valve leaflets fixedly coupled to the stent frame assembly. The peripheral ring fits over a native mitral valve annulus when the prosthesis device is implanted in a native mitral valve. The peripheral ring limits the protrusion of the stent frame assembly into a ventricular chamber and reduces the effect on ventricular outflow or excursion of a native leaflet by such protrusion.