Side-Delivered Mitral Valve Anchoring Tabs
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Solution Overview
Problem
Current transcatheter mitral valve replacement technologies face challenges with regurgitation and material durability issues, requiring expensive materials to withstand the mechanical stresses of heart function, and often necessitate invasive delivery methods.
Innovation Solution
A side-delivered transcatheter mitral valve with an extendable proximal and distal anchoring system, featuring a self-expanding annular support frame, collapsible flow control component, and anchoring tabs that deploy and secure native tissue using a guide wire, allowing for a larger valve diameter to be delivered without an oversized catheter and at a non-acute angle, utilizing Nitinol wire cells and biocompatible materials for durability.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Quantity of substance
If a large-diameter valve is delivered using traditional transcatheter methods, then the valve can replace the native mitral valve, but the delivery catheter becomes oversized and requires acute angle approach which increases procedural complexity and invasiveness
Solution Approach 1:
The delivery system transitions from axial delivery (through the aorta) to transseptal delivery (through the interatrial septum), changing the dimensional approach to reach the mitral valve. This allows large-diameter valves to be delivered through a more direct path without requiring oversized catheters or acute angle maneuvers, as the valve is delivered from the left atrium side rather than having to navigate the aortic arch and descend into the heart
2Ease of operation
If stent-style replacement valves are used, then the valve can be delivered via catheter, but regurgitation and leakage problems persist
Solution Approach 1:
The anchoring tabs are positioned at specific locations (proximal, distal, and anterior commissures) rather than uniformly distributed, allowing targeted engagement with native tissue at critical sealing points. This localized anchoring approach ensures proper valve coaptation and eliminates regurgitation by securing the valve at the three-dimensional corners of the mitral annulus, rather than relying on uniform stent expansion
3Strength
If expensive materials are used to withstand mechanical stresses, then the valve durability improves, but the cost increases
Solution Approach 1:
The anchoring tabs are designed as simple, potentially resorbable structures that perform their anchoring function and then can be absorbed by the body over time, replacing the need for permanent, expensive metal anchoring mechanisms. The tabs provide sufficient mechanical strength during the critical healing period and then naturally degrade, eliminating the need for lifelong expensive materials while maintaining valve security
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
Enables the deployment of a large-diameter mitral valve with reduced regurgitation and improved durability, facilitating a less invasive outpatient procedure while minimizing material costs and mechanical stress, by securely anchoring the valve within the native tissue.
Implementation Method 1
utilizing Nitinol wire cells
Data Source
AI summary
The present invention is directed to a proximal anchoring tab for a side delivered prosthetic mitral valve having an elongated distal tab, where the proximal tab anchors the proximal side of the prosthetic valve using a tab or loop deployed to the A3-P3 (proximal) commissure area of the mitral valve, and wherein the elongated distal tab is extended around the posterior P1-P2 leaflet and/or chordae using a guide wire to capture native mitral leaflet and/or chordae tissue and where withdrawing the guide wire contracts the tab and pins the native posterior tissue against the subannular posterior-side sidewall of the prosthetic valve.