Percutaneous Catheter for Mitral Valve Triangular Resection

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Solution Overview

Problem

Current methods for treating mitral valve regurgitation, particularly in cases of mitral prolapse, often require invasive surgical techniques with high operative mortality and long-term risks, especially in patients with impaired left ventricular function and pulmonary hypertension, and existing percutaneous systems cannot perform triangular resections effectively.

Innovation Solution

A percutaneous medical device employing a single catheter for triangular plication and resection of prolapsed mitral valve leaflets using a grasping tweezer and plicating tweezer within a catheter, allowing for minimally invasive treatment of both posterior and anterior leaflets, and potentially applicable to other valve types, with options for fixation via staples, stitches, or thermal treatments.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If surgical repair or replacement of the mitral valve is performed, then effective treatment of mitral regurgitation is achieved, but operative mortality and surgical risk increase significantly

Engineering Contradiction:
Improveeffectiveness of mitral regurgitation treatmentVSAvoidoperative mortality and surgical risk
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent replaces traditional open surgical mechanical systems with a percutaneous catheter-based system. The catheter delivers specialized tools (grasping tweezer, plicating tweezer, resection tools) through vascular access to perform mitral valve repair without sternotomy, thereby eliminating the high mortality risk associated with open heart surgery while maintaining effective treatment of mitral regurgitation

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The patent introduces a percutaneous catheter as an intermediary device to deliver repair tools to the mitral valve. This intermediary approach allows indirect access to the heart valve through peripheral vascular access, avoiding direct surgical exposure and reducing the harmful effects of sternotomy and cardiopulmonary bypass

Inventive Principle:
Principle #24Intermediary (Mediator)

2Ease of operation

If existing percutaneous tissue repair systems are used, then minimally invasive access is achieved, but triangular resection cannot be performed

Engineering Contradiction:
Improveminimally invasive accessVSAvoidcapability to perform triangular resection
Core Design Contradiction:
Ease of operationVSAdaptability or versatility

Solution Approach 1:

The patent creates a multi-functional percutaneous catheter system that can perform multiple repair techniques including plication, resection, and tissue grasping. The catheter is designed to accommodate various tools (grasping tweezer, plicating tweezer, resection tools) that can be deployed sequentially or selectively based on the specific repair needs, making the system versatile enough to perform triangular resection while maintaining minimally invasive access

Inventive Principle:
Principle #6Universality (Multi-functionality)

3Ease of operation

If traditional surgical techniques are used, then complete control of tissue repair is achieved, but invasive procedures with high mortality are required

Engineering Contradiction:
Improvecontrol of tissue repairVSAvoidinvasive procedures and operative mortality
Core Design Contradiction:
Ease of operationVSObject-affected harmful factors

Solution Approach 1:

The patent employs dynamic, remotely controllable tools within the catheter system. The grasping tweezer and plicating tweezer can be actuated remotely through the catheter to dynamically adjust tissue grasping, plication, and resection in real-time during the procedure, providing complete control over tissue repair while maintaining percutaneous access and avoiding high-mortality open surgery

Inventive Principle:
Principle #15Dynamics

Data Source

PatentEP3244807B1Device for transcatheter heart valve repair under triangular resection technique
Publication Date: 2023.11.22 EPYGON
  • EP3244807B1 patent drawingFigure 1
  • EP3244807B1 patent drawingFigure 2A~2D
  • EP3244807B1 patent drawingFigure 3A~3E

AI summary

Medical device for transcatheter heart valve repair comprising a grasping tweezer (1) and a plicating tweezer (2), said grasping tweezer (1) being adapted to grasp a leaflet rim (3) and said plicating tweezer (2) comprising two rotatable flaps (4,5) and a central shaft (6) around which said flaps (4,5) may rotate in a "butterfly manner", in such a way that the plicating tweezer (2) may adopt a closed or an open configuration. The invention also relates to a method for using this medical device.