Mixed Reality Lab Automation Guidance

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Solution Overview

Problem

Automated laboratory systems experience downtime and errors due to human errors, primarily caused by improper setup and placement of labware, leading to increased costs and reduced efficiency.

Innovation Solution

The implementation of a mixed reality system that provides real-time guidance and feedback to users through augmented reality, using recognizable markers and machine learning algorithms to assist in the setup and configuration of automated laboratory equipment, ensuring accurate placement and operation of labware and instruments.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If automated laboratory systems are used to increase productivity, then output per unit time is improved, but human error from improper setup and placement of labware increases system failures and downtime

Engineering Contradiction:
Improveoutput per unit timeVSAvoidsystem failure rate
Core Design Contradiction:
ProductivityVSReliability

Solution Approach 1:

The system uses computer vision to continuously monitor labware placement and provides real-time feedback to users through a graphical user interface, alerting them to improper placement before it causes system failures. This closed-loop feedback mechanism prevents errors that would otherwise lead to downtime while maintaining high automation productivity.

Inventive Principle:
Principle #23Feedback

Solution Approach 2:

The patent replaces manual visual inspection and physical verification of labware placement with an automated computer vision system using cameras and machine learning algorithms. This substitution eliminates human error in setup verification while maintaining the productivity benefits of automation.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

2Adaptability or versatility

If complex automated laboratory equipment is deployed to enhance experimental capabilities, then research effectiveness is improved, but setup complexity and configuration difficulty increase

Engineering Contradiction:
Improveexperimental capabilitiesVSAvoidsetup and configuration ease
Core Design Contradiction:
Adaptability or versatilityVSEase of operation

Solution Approach 1:

The system automatically detects and verifies labware placement using computer vision, eliminating the need for users to manually configure complex settings. The automated verification process makes the system self-sufficient in checking its own setup, reducing the operational burden on users while maintaining versatile experimental capabilities.

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The graphical user interface uses color-coded visual feedback to indicate the status of labware placement (e.g., green for correct, red for incorrect). This visual signaling system simplifies the complex verification process into intuitive color cues, making operation easier without reducing experimental versatility.

Inventive Principle:
Principle #32Color changes

3Reliability

If real-time monitoring and guidance systems are implemented to reduce errors, then reliability is improved, but device complexity and computational requirements increase

Engineering Contradiction:
Improveerror reductionVSAvoidsystem architecture complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The system introduces a computer vision system as an intermediary layer between the physical labware and the automated laboratory equipment. This intermediary automatically verifies placement and communicates status to the control system, improving reliability without requiring direct complex integration between all system components.

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The computer vision system creates digital copies (images) of the physical labware placement, which are then processed by machine learning algorithms to verify correctness. This copying approach simplifies the monitoring architecture by separating the visual detection function from the control logic, reducing overall system complexity.

Inventive Principle:
Principle #26Copying

Data Source

PatentUS12125145B2Systems and methods for implemented mixed reality in laboratory automation
Publication Date: 2024.10.22 BEAM THERAPEUTICS INC
  • US12125145B2 patent drawing
  • US12125145B2 patent drawing
  • US12125145B2 patent drawing

AI summary

Systems and methods for providing instructing mixed reality overlays for configuring automation protocols in laboratory processes using computing systems include receiving an image from an image feed of an environment. Component markers in the image of the environment are detected and matched with an associated environment component, an environment component action or both. The environment component or environment component action, or both are selected and an animation of an instruction is rendered. An overlay of the animation is caused to display in an augmented reality device associated with a user to appear in a location in the environment of the environment component or environment component action, or both.