ML Triage for Ophthalmic Image Screening

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Solution Overview

Problem

Current telemedicine workflows for ocular disease screening are inefficient, leading to delays in patient examination and treatment, particularly due to the latency in graders becoming available to review digital images.

Innovation Solution

The implementation of a diagnostic platform that uses machine learning models to analyze digital images from retinal cameras, stratifying patients for further examination based on the severity of their ocular diseases, thereby prioritizing those who need urgent attention.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of operation

If telemedicine workflows are used for ocular disease screening, then patient examination can be conducted remotely, but delays occur due to latency in graders becoming available

Engineering Contradiction:
Improveremote examination capabilityVSAvoidexamination delay
Core Design Contradiction:
Ease of operationVSLoss of time

Solution Approach 1:

The system performs preliminary triage and prioritization of digital images using automated analysis before graders review them. Images are pre-sorted by urgency and patient risk stratification, so when graders become available, they immediately process the most critical cases first, eliminating waiting delays.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

An automated prioritization system acts as an intermediary between image capture and grader review. This intermediary layer analyzes images, stratifies patients by risk level, and queues cases appropriately, bridging the gap between remote image capture and human grader availability.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Reliability

If all patients are examined equally by healthcare professionals, then comprehensive care is provided, but resource utilization is inefficient

Engineering Contradiction:
Improvecomprehensive careVSAvoidresource utilization efficiency
Core Design Contradiction:
ReliabilityVSProductivity

Solution Approach 1:

Different levels of review are applied to different patients based on their risk stratification. High-risk patients receive expedited comprehensive review by specialists, while low-risk patients receive automated screening with less intensive human review, optimizing resource allocation while maintaining comprehensive care for those who need it most.

Inventive Principle:
Principle #3Local quality

Solution Approach 2:

The patient population is segmented into risk strata based on automated analysis of digital images and clinical data. This segmentation allows the system to apply different examination intensities and resource allocations to different segments, improving overall productivity while maintaining reliability for high-risk groups.

Inventive Principle:
Principle #1Segmentation

3Productivity

If automated machine learning analysis is implemented, then processing speed increases, but diagnostic accuracy may be reduced compared to human professionals

Engineering Contradiction:
Improveprocessing speedVSAvoiddiagnostic accuracy
Core Design Contradiction:
ProductivityVSMeasurement precision

Solution Approach 1:

The system merges automated machine learning analysis with human professional review in a hybrid workflow. AI performs initial rapid screening and prioritization at high speed, then human graders review cases with AI-generated recommendations, combining the speed advantages of automation with the accuracy of human expertise.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The system incorporates feedback loops where human grader decisions are used to refine and retrain the machine learning models. This continuous feedback improves diagnostic accuracy over time while maintaining high processing speeds, as the AI learns from human expert corrections and adjustments.

Inventive Principle:
Principle #23Feedback

Data Source

PatentUS20250174354A1Workflow enhancement in screening of ophthalmic diseases through automated analysis of digital images enabled through machine learning
Publication Date: 2025.05.29 VERILY HEALTH INC
  • US20250174354A1 patent drawing
  • US20250174354A1 patent drawing
  • US20250174354A1 patent drawing

AI summary

Introduced here are approaches to assessing digital images generated during image capture sessions using a machine learning model so as to stratify patients for examination. By applying the machine learning model to the digital images, the patients that are most in need of further examination can be identified to graders. For example, outputs produced by the diagnostic model may trigger the generation and transmission of notifications for patients that are deemed to warrant further examination.