Mobile Device Assay Analysis Using Image Capture
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Solution Overview
Problem
Existing assays that rely on visual assessment of color changes for test results are prone to variability due to operator acuity, limiting precision, accuracy, and reproducibility, and often lack formal records for quality or evidential purposes, while existing electronic solutions are complex, bulky, and costly.
Innovation Solution
A portable testing apparatus using a mobile device with a processor and image capture capability to process and quantify assay results by measuring color or pattern variations, allowing for quantitative analysis and transmission of data via networks, and including features like image optimization, noise reduction, and real-time feedback.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Ease of operation
If visual assessment by operator is used, then ease of operation is improved, but measurement precision deteriorates
Solution Approach 1:
The patent replaces the mechanical/visual assessment system with an electronic image capture and processing system. A mobile device captures images of the assay, and software algorithms automatically analyze color changes, replacing the operator's visual assessment with automated digital image processing to eliminate human variability while maintaining ease of use.
Solution Approach 2:
The patent creates a digital copy of the visual assay result through image capture. Instead of directly interpreting the visual color change, the system captures an image copy of the assay, processes it digitally, and derives quantitative results from the digital representation, thereby eliminating operator dependency while preserving the original test's simplicity.
2Measurement precision
If electro-optic instrument is used, then measurement precision is improved, but device complexity worsens
Solution Approach 1:
The patent applies a universal mobile device (smartphone, tablet, or laptop with camera) that can perform multiple functions including image capture, image processing, and result analysis. This multi-functional approach replaces specialized electro-optic instruments, achieving measurement precision through software algorithms while eliminating the need for complex, application-specific hardware.
Solution Approach 2:
The patent substitutes complex electro-optic measurement systems with a simpler mobile device equipped with a camera and processing software. The electronic image processing algorithms replace the complex optical measurement mechanisms, achieving comparable or superior precision with significantly reduced hardware complexity.
3Measurement precision
If electro-optic instrument is used, then measurement precision is improved, but portability worsens
Solution Approach 1:
The patent utilizes a universal mobile device that is inherently portable and can be easily transported. The same device that captures images also processes them and stores results, eliminating the need for bulky, specialized measurement equipment. This multi-functional portable device achieves measurement precision through software rather than complex hardware.
4Measurement precision
If custom electro-optic instrumentation is used, then measurement precision is improved, but manufacturing cost worsens
Solution Approach 1:
The patent employs inexpensive, commercially available mobile devices instead of costly custom-built electro-optic instruments. The use of off-the-shelf mobile devices with existing cameras and processing capabilities dramatically reduces hardware costs while achieving measurement precision through software algorithms. The assay components themselves remain disposable, while the measurement system becomes a reusable, low-cost mobile device.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
Enables precise, portable, and cost-effective quantitative analysis of assay results, reducing operator variability and eliminating the need for custom hardware, with the ability to store and transmit data for quality control and record-keeping.
Implementation Method 1
a portable device comprising a processor and an image capture device, wherein the processor is configured to process data captured by the image capture device
Implementation Method 2
the reagent being reactive to an applied test sample by developing a colour or pattern variation
Data Source
AI summary
A testing apparatus for performing an assay, the testing apparatus comprising: a receptacle (2) containing a reagent, the reagent being reactive to an applied test sample by developing a colour or pattern variation; a portable device (1), e.g. a mobile phone or a laptop, comprising a processor and an image capture device (3), wherein the processor is configured to process data captured by the image capture device and output a test result for the applied test sample.