Mobile Diagnostic Structure With Sterile Sample Transfer
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Solution Overview
Problem
Current nucleic acid-based diagnostic systems require specialized equipment and environments, making it difficult to deploy and operate them easily in various locations, especially in areas without existing infrastructure, which can hinder disease monitoring and prevention efforts.
Innovation Solution
A mobile diagnostic structure with a partitioned housing containing a preparation room, analysis room, and transfer modules that include UV radiation and air pressure adjustment units to ensure sterile sample handling and prevent contamination, allowing for the deployment of nucleic acid-based diagnostics in any location.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If specialized equipment and environments are used for nucleic acid-based diagnostics, then test precision and reliability are improved, but ease of deployment and operation deteriorates
Solution Approach 1:
The diagnostic system is divided into separate functional modules including a preparation room for sample processing, an analysis room for nucleic acid detection, and a transfer module for sample transport. This segmentation allows each module to be optimized for its specific function while maintaining overall system reliability, and enables flexible deployment in different locations.
Solution Approach 2:
A transfer module with sterile barriers and air pressure control acts as an intermediary between the preparation room and analysis room. This intermediary maintains the integrity of the diagnostic environment by preventing contamination during sample transfer, thus preserving test precision while enabling separate operation of preparation and analysis functions.
2Object-affected harmful factors
If strict environmental control measures are implemented, then contamination prevention is improved, but device complexity increases
Solution Approach 1:
Air pressure control systems are implemented in the transfer module to create pressure differentials between the preparation room and analysis room. This pneumatic control prevents contamination by ensuring air flows from cleaner to less clean areas, providing effective contamination prevention through relatively simple pressure regulation mechanisms.
Solution Approach 2:
The transfer module employs sterile barriers and controlled atmospheric conditions to create an inert environment that prevents contamination. By maintaining a controlled atmosphere with appropriate air pressure and sterile filtering, the system prevents harmful factors without requiring overly complex environmental control systems.
3Reliability
If separate preparation and analysis rooms are used, then sample integrity is improved, but ease of operation deteriorates
Solution Approach 1:
A transfer module serves as an intermediary between the preparation room and analysis room, providing a controlled pathway for sample transport. This intermediary maintains sample integrity by preventing contamination during transfer while keeping the operational process straightforward through automated or guided sample movement procedures.
Solution Approach 2:
The sample transfer function is extracted from the main diagnostic operations and placed in a dedicated transfer module. This extraction allows sample integrity to be maintained by isolating the transfer process in a controlled environment, while the rest of the diagnostic operations can proceed with operational simplicity in their respective rooms.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
Enables the performance of nucleic acid-based diagnostics anywhere, reducing the risk of contamination and infection, and ensuring precise results through optimal device calibration, thus facilitating comprehensive disease monitoring and prevention.
Implementation Method 1
The transfer module may further include an ultraviolet (UV) radiator radiating UV light to the opening for the transfer module, in a state in which the opening for the transfer module is opened by the door unit
Implementation Method 2
an air curtain blocking an air flow through the opening for the transfer module between the preparation room and the analysis room
Implementation Method 3
The mobile diagnostic structure may further comprise an air pressure adjustment unit adjusting an internal air pressure of the middle chamber relative to an internal air pressure of the preparation room or an internal air pressure of the analysis room
Data Source
AI summary
According to an embodiment, a mobile diagnostic structure comprises a housing including a space therein; a partitioning module partitioning the space to include a preparation room and an analysis room; an inlet module providing an incoming path from an outside to the preparation room for a raw sample; and a transfer module providing a transfer path from the preparation room to the analysis room, for a pre-treated sample which is a result of pre-treating the raw sample in the preparation room.