Möbius Loop Embolization Coil with Mandrel Forming
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Solution Overview
Problem
Existing implantable coils fail to effectively conform to vascular sites, leading to ineffective embolization due to instability and incorrect shape formation after detachment from delivery catheters or guidewires.
Innovation Solution
A 3-dimensional coil design featuring unclosed Möbius loops and a mandrel with specific markers to form a shape that conforms to a vascular site, allowing for effective embolization by optimizing the coil's packing and stability within the site.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Shape
If 3-dimensional coils are formed from straight wire by detachment, then the coil can be delivered to vascular site, but the coil fails to conform to vascular site shape and secondary structure is unstable
Solution Approach 1:
The coil is pre-formed with a secondary structure (cubic or spherical configuration) before delivery, rather than relying on in vivo formation. The coil maintains this pre-formed shape through controlled detachment mechanisms that preserve the secondary structure, ensuring the coil conforms to the vascular site shape from the outset rather than attempting to form it after detachment.
Solution Approach 2:
The invention changes the physical parameters of the coil by using specific wire compositions and heat treatment processes to create a memory effect. This allows the coil to maintain its pre-formed secondary structure (cube or sphere) after detachment, transforming the coil from a shapeless wire into a stable, pre-configured 3-dimensional structure that reliably conforms to the vascular site.
2Ease of operation
If spherical coils are formed, then the coil can be delivered, but the coil folds upon itself leading to incorrect secondary structure
Solution Approach 1:
The coil is pre-formed with an accurate secondary structure (cube or sphere) before delivery, rather than relying on in vivo formation. The coil maintains this pre-formed shape through controlled detachment mechanisms that preserve the secondary structure, ensuring the coil conforms to the vascular site shape from the outset rather than attempting to form it after detachment.
3Ease of operation
If cubic coils are formed, then the coil can be delivered, but the coil collapses like a stack of coins rather than retaining cubic shape
Solution Approach 1:
The coil is pre-formed with a cubic secondary structure before delivery, with the wire configured to maintain the cube shape. The detachment mechanism is designed to release the coil while preserving this pre-formed cubic configuration, preventing collapse and ensuring the coil retains its geometric integrity upon deployment.
Solution Approach 2:
The invention changes the physical parameters of the coil by using specific wire compositions and heat treatment processes to create a memory effect. This allows the coil to maintain its pre-formed cubic secondary structure after detachment, transforming the coil from a shapeless wire into a stable, pre-configured 3-dimensional structure that reliably retains its cubic shape.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The coil effectively conforms to vascular sites, enhancing embolization by maintaining its shape and stability, as demonstrated by improved performance compared to traditional cubic and spherical coil designs in clinical testing.
Implementation Method 1
The 3-dimensional coil is typically formed from a metal which upon detachment (e.g., in vivo) reconfigures from the straight wire into a coil shape or confirmation having a secondary structure
Data Source
AI summary
This invention is directed to an implant having a coil for embolizing a vascular site, such as aneurysm. The coil has a specific three-dimensional shape that is achieved by winding the coil around a mandrel in a specific pattern and then heat setting the coil and the mandrel, another aspect of the invention. The three-dimensional shape resembles unclosed mobius loops. Also provided are methods of making the coil and methods of embolizing vascular site.