Modified Ascaroside Compositions for Extended Soil Release
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Solution Overview
Problem
Ascarosides are prone to rapid biodegradation in soil and metabolic breakdown, leading to unreliable applications as seed treatments or in-furrow applications, as they may degrade before being taken up by crop plants, thus affecting the intended plant response.
Innovation Solution
Development of structurally and physically modified ascarosides, including ascaroside-based oligomers, polymers, and compositions compounded with organic or inorganic materials, designed for extended release and reduced biodegradation.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If ascarosides are applied as seed treatments or in-furrow applications, then plant resistance to pathogens is increased, but the ascarosides degrade rapidly in soil before being taken up by plants
Solution Approach 1:
The ascaroside molecules are pre-modified with biodegradable polymer conjugates or encapsulated in controlled-release formulations before application. This preliminary action protects the ascarosides from rapid biodegradation in soil and enables sustained release over time, ensuring the compounds remain active long enough to be taken up by germinating plants and elicit the desired defense response.
Solution Approach 2:
The chemical structure of ascarosides is modified by conjugating them with biodegradable polymers or incorporating them into controlled-release matrices. These parameter changes alter the degradation kinetics and release profile of the ascarosides, transforming them from rapidly degrading molecules into sustained-release agents that maintain effective concentrations throughout the plant growth period.
2Stability of the object's composition
If structurally modified ascarosides are used, then biodegradation is reduced and release is extended, but molecular complexity increases
Solution Approach 1:
The invention combines ascaroside molecules with biodegradable polymer materials to create composite structures. These composites leverage the stability and controlled degradation properties of the polymer while maintaining the bioactivity of the ascaroside core. The polymer-ascaroside conjugates or encapsulation systems provide enhanced stability against biodegradation without requiring complex modifications to the ascaroside molecule itself.
Data Source
AI summary
This application relates to modified release compounds and compositions comprising one or more ascarosides, which can be applied to plants to provide increased disease resistance. Certain compounds are structurally modified ascarosides, e.g., in the form of ascaroside-containing polymers. Certain compounds are physically modified ascarosides in the form of one or more ascarosides compounded with organic and/or inorganic components.