Modified Microorganisms for High-Value Fermentation Residuals

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Solution Overview

Problem

Current ethanol production schemes are not optimized, with little research focused on enhancing the value output of fermentation residuals such as distillers grain, which is a significant portion of the animal feed market, affecting the profitability of ethanol facilities.

Innovation Solution

The use of modified microorganisms in fermentation reactions to produce fermentation residuals with enhanced nutritional content, including essential amino acids, vitamins, and other nutrients, which can be used as high-value animal feed or food supplements.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Quantity of substance

If conventional fermentation schemes are used, then ethanol production is maintained, but the commercial value of fermentation residuals is low

Engineering Contradiction:
Improvecommercial value of fermentation residualsVSAvoidprofitability of ethanol facility
Core Design Contradiction:
Quantity of substanceVSProductivity

Solution Approach 1:

The patent applies parameter changes by modifying the microbial strain parameters through genetic engineering to overproduce essential amino acids (lysine, methionine, threonine) during fermentation. This changes the compositional parameters of the fermentation residual from conventional low-nutrient distillers grains to high-nutrient DDGS with enhanced amino acid content, thereby increasing commercial value while maintaining ethanol production

Inventive Principle:
Principle #35Parameter changes

2Productivity

If research focuses on improving ethanol production, then ethanol output increases, but the value output of fermentation residuals is not enhanced

Engineering Contradiction:
Improveethanol productionVSAvoidvalue output of fermentation residuals
Core Design Contradiction:
ProductivityVSQuantity of substance

Solution Approach 1:

The patent implements multi-functionality by engineering microorganisms to perform dual functions: (1) conventional ethanol fermentation and (2) overproduction of essential amino acids. The modified microbial strain simultaneously produces ethanol as the primary fermentation product and accumulates essential amino acids (lysine, methionine, threonine) in the residual biomass, allowing one fermentation process to yield two valuable products

Inventive Principle:
Principle #6Universality (Multi-functionality)

3Productivity

If distillers grain sales lag behind ethanol production growth, then facility profitability is significantly affected

Engineering Contradiction:
Improveethanol production growthVSAvoiddistillers grain sales volume
Core Design Contradiction:
ProductivityVSQuantity of substance

Solution Approach 1:

The patent resolves this imbalance by changing the quality parameters of distillers grain through genetic modification of fermentation microbes. The enhanced amino acid profile (particularly lysine, methionine, and threonine) transforms ordinary distillers grains into premium DDGS that commands higher market value and demand, allowing sales volume to keep pace with ethanol production growth

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach increases the commercial value of fermentation residuals, improving the profitability of ethanol facilities by creating a higher-value product that can be marketed as animal feed or food supplements, while maintaining ethanol production levels.

Implementation Method 1

performing a fermentation reaction with the use of a modified microorganism

Methodology Applied
Scientific EffectFermentation: Fermentation

Data Source

PatentUS7309602B2Compositions and methods for producing fermentation products and residuals
Publication Date: 2007.12.18 GEVO INC
  • US7309602B2 patent drawing
  • US7309602B2 patent drawing

AI summary

The present invention provides compositions and methods designed to increase value output of a fermentation reaction. In particular, the present invention provides a business method of increasing value output of a fermentation plant. The present invention also provides a modified fermentation residual of higher commercial value. Also provided in the present invention are complete animal feeds, nutritional supplements comprising the subject ferment residuals. Further provided by the present invention is a method of performing fermentation, a modified fermentative microorganism and a genetic vehicle for modifying such microoganism.