Modified Strigolactone Derivatives for Seed Germination Under Abiotic Stress
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Solution Overview
Problem
Current strigolactone derivatives are not effective in promoting seed germination under various stress conditions, particularly drought, cold, salt, and osmotic stress, and do not provide improved crop growth and yield.
Innovation Solution
Development of novel strigolactone derivatives with specific structural modifications, such as compounds of formula (I), which include oxygen or N-R1 as part of the structure, offering improved tolerance to abiotic stress, enhanced seed germination, and better crop growth regulation.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If known strigolactone derivatives are used, then plant growth regulation and seed germination promotion are achieved, but effectiveness under abiotic stress conditions (drought, cold, salt, osmotic stress) is insufficient
Solution Approach 1:
The patent modifies the chemical structure of strigolactone derivatives by changing parameters such as substituting hydrogen atoms with fluorine or trifluoromethyl groups, and modifying the R1 and R2 substituents on the cyclohexene ring. These structural parameter changes enhance the compound's stability and biological activity under abiotic stress conditions while maintaining or improving seed germination promotion effects
Solution Approach 2:
The invention creates composite chemical structures by combining the strigolactone core with various substituent groups (fluorine, trifluoromethyl, alkyl groups). These composite molecular structures provide both the plant growth regulation activity of strigolactone and enhanced stress tolerance properties from the stabilizing substituent groups
2Productivity
If strigolactone derivatives are applied, then seed germination is promoted, but uniformity and synchronicity of germination are insufficient
Solution Approach 1:
By optimizing the stereochemical parameters and substituent positions on the strigolactone molecule, the patent achieves more consistent interaction with plant receptors, resulting in uniform and synchronous germination responses across seed populations while maintaining high germination rates
3Productivity
If existing strigolactone compounds are used, then some plant growth regulation is achieved, but crop yield improvement and stress tolerance are insufficient
Solution Approach 1:
The patent introduces fluorine and trifluoromethyl substituents at specific positions on the strigolactone molecule, which enhance the compound's metabolic stability and bioavailability. These parameter changes enable the compound to effectively improve crop yield while providing robust protection against abiotic stresses such as drought, cold, salt, and osmotic stress
Solution Approach 2:
The patent converts the vulnerability of plants to abiotic stress into an opportunity by using modified strigolactone derivatives that activate stress response pathways. The compounds help plants convert stress conditions into beneficial adaptive responses, improving both yield and stress tolerance simultaneously
Data Source
AI summary
The present invention relates to new compounds of formula (I) for the promotion of seed germination, to processes for preparing the compounds, to seeds comprising the compounds, to seed germination promoting compositions comprising the compounds and to methods of using the compounds for promoting the germination of seeds. In particular, the compounds are useful in promoting germination of corn under cold stress conditions.