Modular Beta-Particle Detector for Minimally Invasive RGS

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Solution Overview

Problem

Existing mini-invasive surgery probes are unable to effectively detect beta radiation due to their opacity to beta particles, while maintaining the necessary characteristics for miniaturization, biocompatibility, and mechanical resistance, which are crucial for robotic surgery applications.

Innovation Solution

A modular, compact detector structure is developed with a sequentially assembled design, incorporating an ambient light absorber, scintillator, light detector, and housing, optimized for beta-particle detection, ensuring high efficiency and miniaturization, while meeting surgical constraints such as sterilizability and biocompatibility.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If traditional probes use high-density materials (tungsten, titanium) for gamma detection optimization, then gamma detection performance and resolution are improved, but the device becomes completely opaque to beta radiation

Engineering Contradiction:
Improvegamma detection performanceVSAvoidbeta radiation opacity
Core Design Contradiction:
Measurement precisionVSObject-affected harmful factors

Solution Approach 1:

The probe is divided into functionally separate segments: a front detection section with low-density materials for beta detection, and a rear section with high-density materials for gamma detection. This segmentation allows each segment to optimize its specific detection function without compromising the other.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

Different materials with specific properties are applied to different regions of the probe. The front detection area uses low-density materials (plastic, aluminum) that are transparent to beta particles, while the rear section uses high-density materials (tungsten, titanium) for gamma detection. This local differentiation resolves the contradiction between beta transparency and gamma detection performance.

Inventive Principle:
Principle #3Local quality

2Length of moving object

If the probe transverse dimension is reduced to less than 11-12 mm for mini-invasive surgery access, then the device can be inserted through standard trocar access points, but detection efficiency and signal resolution may be compromised

Engineering Contradiction:
Improveprobe transverse dimensionVSAvoiddetection efficiency
Core Design Contradiction:
Length of moving objectVSMeasurement precision

Solution Approach 1:

The probe incorporates a nested structure where the light detector is positioned within or adjacent to the scintillator material. This nesting allows maximum detection efficiency within a compact footprint, enabling the probe to maintain small dimensions while preserving detection capability.

Inventive Principle:
Principle #7Nested doll (Nesting)

Solution Approach 2:

The probe uses thin-film scintillator layers and compact light detector structures that maintain detection efficiency while minimizing the overall probe diameter. This allows the probe to fit through standard trocar access points without sacrificing detection performance.

Inventive Principle:
Principle #30Flexible shells and thin films

3Reliability

If the probe uses external surgical steel covering for sterilizability, biocompatibility, and mechanical strength, then these requirements are fulfilled, but the probe becomes completely opaque to beta radiation

Engineering Contradiction:
Improvesterilizability and biocompatibilityVSAvoidbeta radiation opacity
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The protective covering is segmented into a front window area and a rear body. The front window uses thin, beta-transparent materials that allow beta particles to pass through while still providing protection and maintaining sterility. The rear body uses surgical steel for structural integrity and biocompatibility.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

Different material properties are applied to different parts of the covering. The front detection window uses materials with low atomic number and thin thickness that are transparent to beta radiation, while the rear structural portions use surgical steel for strength and biocompatibility. This local differentiation resolves the contradiction between protection and beta transparency.

Inventive Principle:
Principle #3Local quality

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The detector achieves clinically relevant beta-radiation detection efficiency, enabling effective tumor identification in mini-invasive surgeries by reducing tissue penetration and minimizing interference from healthy organs, thus extending the applicability of Radio-Guided Surgery to previously inaccessible anatomical regions.

Implementation Method 1

incorporating an ambient light absorber, scintillator, light detector, and housing, optimized for beta-particle detection

Methodology Applied
Scientific EffectScintillation: Scintillation

Implementation Method 2

light detector, and housing, optimized for beta-particle detection

Methodology Applied
Scientific EffectPhotoelectric effect: Photoelectric Effect

Implementation Method 3

incorporating an ambient light absorber, scintillator, light detector, and housing, optimized for beta-particle detection

Methodology Applied
Scientific EffectLight absorption: Absorption (EM radiation)

Data Source

PatentUS20250298156A1Particle Detector Device Adapted for Application in Minimally Invasive Nuclear Medicine Radio-Guided Surgery (RGS), and Method of Manufacturing the Device
Publication Date: 2025.09.25 ISTITUTO NAZIONALE DI FISICA NUCLEARE
  • US20250298156A1 patent drawing
  • US20250298156A1 patent drawing
  • US20250298156A1 patent drawing

AI summary

Beta-particle detector device adapted for applications of mini-invasive radio-guided surgery, the device being provided with an outer shell, the outer shell having a front element, through which incident radiation enters when in use, and a rear element, through which electric wires come out, which are adapted to transport an electric signal when in use. The device has a sequentially assembled modular structure and includes the following components, adapted to be inserted, when assembled, in the outer shell: an ambient light absorber; a scintillator, positioned downstream of the absorber; a first housing for the scintillator; a light detector positioned downstream of said scintillator; a second housing for the light detector; and a cable holder positioned downstream of the second housing along the direction of the light, and adapted to contain said electric wires and let them exit the device.