Modular Detection System with Lock-In Amplifier for Low Concentration Analysis

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Solution Overview

Problem

Existing portable and modular detection systems are not truly portable or modular, and they fail to reliably detect and measure low concentrations of analytes due to low signal-to-noise ratios and limited modularity, making them ineffective for rapid and accurate chemical analysis.

Innovation Solution

A portable and modular detection system comprising an electromagnetic radiation source, optical elements removably attached to an alignment rail, a photodetector, and a lock-in amplifier, which allows for the collection and amplification of electromagnetic radiation signals from analytes, enabling detection of low concentrations with improved signal-to-noise ratios and modularity.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Weight of moving object

If prior art portable detection systems are used, then device portability is improved, but detection capability for low concentrations of analytes deteriorates

Engineering Contradiction:
Improvedevice portabilityVSAvoiddetection capability for low concentrations
Core Design Contradiction:
Weight of moving objectVSMeasurement precision

Solution Approach 1:

The detection system is divided into separate functional modules (light source module, optical element module, photodetector module, lock-in amplifier module) that can be independently replaced and configured. This segmentation allows optimization of each module's performance while maintaining overall system portability, resolving the contradiction between device size and detection capability.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The system employs a lock-in amplifier that changes the detection parameter from direct intensity measurement to phase-sensitive detection. This parameter transformation enables the system to achieve high measurement precision for low concentrations while maintaining a compact portable form factor.

Inventive Principle:
Principle #35Parameter changes

2Adaptability or versatility

If prior art modular detection systems are used, then component replaceability is improved, but signal-to-noise ratio deteriorates

Engineering Contradiction:
Improvecomponent replaceabilityVSAvoidsignal-to-noise ratio
Core Design Contradiction:
Adaptability or versatilityVSReliability

Solution Approach 1:

The system uses standardized mounting rails and interfaces that enable modular replacement of optical elements while maintaining precise alignment. This segmentation allows component versatility without compromising the signal-to-noise ratio, as each module can be independently optimized.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The lock-in amplifier incorporates feedback mechanisms that continuously monitor and adjust the detection signal to maintain optimal signal-to-noise ratio. This feedback control ensures that modular reconfiguration of optical elements does not degrade detection reliability.

Inventive Principle:
Principle #23Feedback

3Measurement precision

If detection sensitivity is improved for low concentrations, then measurement precision is improved, but device complexity increases

Engineering Contradiction:
Improvedetection sensitivityVSAvoidsystem complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The system merges the light source, optical elements, photodetector, and lock-in amplifier into an integrated modular platform. This combining approach achieves high detection sensitivity while managing complexity through standardized interfaces and compact packaging, as the modules work together as a unified system.

Inventive Principle:
Principle #5Merging (Combining)

4Measurement precision

If optical path length is extended to improve detection, then measurement precision is improved, but device size increases

Engineering Contradiction:
Improvedetection accuracyVSAvoiddevice size
Core Design Contradiction:
Measurement precisionVSVolume of moving object

Solution Approach 1:

The system uses a compact optical configuration that extends the effective optical path length through multiple reflections and transmissions within a small volume. By utilizing three-dimensional optical routing rather than linear extension, the system achieves improved detection accuracy without increasing the overall device footprint.

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The system effectively detects and measures low concentrations of analytes with enhanced signal-to-noise ratios and modularity, allowing for rapid and accurate chemical analysis in a compact, handheld format.

Implementation Method 1

detecting the emitted or reflected electromagnetic radiation, such as fluorescence, from the analyte

Methodology Applied
Scientific EffectElectromagnetic radiation emission: Fluorescence

Implementation Method 2

converting the reflected or emitted electromagnetic radiation to a voltage signal

Methodology Applied
Scientific EffectPhotoelectric conversion: Photoelectric Effect

Implementation Method 3

using phase sensitive detection to provide an amplified voltage signal

Methodology Applied
Scientific EffectPhase sensitive detection: Homodyne Detection

Data Source

PatentUS7602307B1Portable modular detection system
Publication Date: 2009.10.13 SANDIA NAT LAB
  • US7602307B1 patent drawing
  • US7602307B1 patent drawing
  • US7602307B1 patent drawing

AI summary

Disclosed herein are portable and modular detection devices and systems for detecting electromagnetic radiation, such as fluorescence, from an analyte which comprises at least one optical element removably attached to at least one alignment rail. Also disclosed are modular detection devices and systems having an integrated lock-in amplifier and spatial filter and assay methods using the portable and modular detection devices.