Modular Laboratory System for Automated Sample Processing
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Solution Overview
Problem
Conventional medical laboratory systems face inefficiencies in processing patient samples due to manual handling, limited automation, and compatibility issues with various sample tube types and analyzers from different manufacturers, leading to increased downtime and reduced throughput.
Innovation Solution
A modular laboratory system with five basic functional units (manager, centrifuge, aliquotter, output/sorter, and storage units) that uses universal components and intelligent scheduling to automate sample processing, prioritize urgent samples, and optimize sample routing, enabling efficient handling of diverse sample types and analyzers.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Productivity
If manual handling is used for sample transport between standalone stations, then flexibility in laboratory layout is maintained, but processing time increases and productivity decreases
Solution Approach 1:
The system is divided into modular functional units (input module, centrifuge module, aliquotter module, output module, storage module) that can be independently configured and connected via standardized conveyance interfaces, allowing automation without requiring complete system replacement
Solution Approach 2:
The conveyance system uses universal sample carriers and standardized interfaces that can transport various sample tube types (different manufacturers, sizes, configurations) through different modules, enabling one system to handle diverse sample processing needs
2Adaptability or versatility
If conventional recappers are used that support only one type of cap, then device complexity is reduced, but adaptability to different sample tube types decreases
Solution Approach 1:
The recapper system dynamically adapts to different cap types by using vision systems to identify cap characteristics and automatically adjusting recapping parameters (force, speed, positioning), allowing a single device to handle multiple cap types without manual reconfiguration
Solution Approach 2:
The recapper modifies operational parameters (gripper force, approach speed, capping torque) based on detected sample tube and cap characteristics, enabling the same hardware to accommodate varying sample container specifications
3Loss of information
If image analysis algorithms are used for single object identification in hold racks, then detection precision is achieved, but the ability to identify multiple object details is lost
Solution Approach 1:
The system transitions from 2D top-view image analysis to multi-dimensional characterization by capturing images from multiple angles (front, back, top, bottom) and combining them with depth data from the rack structure, enabling comprehensive identification of multiple objects and their features
4Productivity
If conventional sample tube markers are used that require manual application, then ease of operation is maintained for simple labeling, but productivity decreases and time is lost
Solution Approach 1:
Manual mechanical application of physical markers (stickers, labels) is replaced with automated optical marking systems that can print or project identification information directly onto sample tubes, eliminating manual intervention while maintaining clear visibility
5Productivity
If conventional sample volume detection devices are used that are manually operated, then measurement precision is achieved, but productivity decreases due to manual operation requirements
Solution Approach 1:
The sample volume detection system operates autonomously by integrating optical sensors and image analysis capabilities directly into the conveyance path, allowing samples to be measured automatically during transport without requiring manual removal to separate detection devices
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The system significantly reduces manual handling, minimizes downtime, and maximizes throughput by automating sample processing and prioritizing urgent samples, while accommodating different sample types and analyzers, thereby enhancing efficiency and accuracy.
Implementation Method 1
The centrifuge unit includes a centrifuge capable of centrifuging a sample
Data Source
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Figure 2(b)
AI summary
An analytical laboratory system and method for processing samples is disclosed. The system includes a manager unit, as well as an aliquotter unit and a centrifuge unit.