Modular Multi-Biochip PCR Layout for Simultaneous Testing

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Solution Overview

Problem

Existing PCR apparatuses are limited to performing PCR inspections on a single sample at a time, requiring multiple units for simultaneous testing, which increases costs and complicates the process, and are structurally weak with fixed control modules that are difficult to repair.

Innovation Solution

A modular simultaneous diagnosis PCR system with multiple biochips, heating/cooling, light source, and detection modules controlled by a single control module, allowing simultaneous PCR inspections and featuring a rotatable display panel for easy maintenance and reduced duplication of components.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If multiple PCR apparatuses are used to perform simultaneous PCR inspections on multiple samples, then the testing capacity is improved, but the cost and device complexity increase

Engineering Contradiction:
Improvetesting capacityVSAvoiddevice complexity
Core Design Contradiction:
ProductivityVSDevice complexity

Solution Approach 1:

The patent combines multiple PCR modules (first PCR module and second PCR module) into a single integrated apparatus, allowing simultaneous PCR inspections on multiple samples while sharing common components such as the control module, display panel, and main body housing. This merging approach increases testing capacity without proportionally increasing device complexity.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The control module and display panel serve multiple functions by controlling and displaying information for both the first and second PCR modules simultaneously. This multi-functionality allows a single set of control components to manage multiple testing channels, improving productivity while avoiding the need for separate control systems for each module.

Inventive Principle:
Principle #6Universality (Multi-functionality)

2Stability of the object's composition

If a fixed control module is used in the PCR apparatus, then the structural stability is improved, but the ease of repair deteriorates

Engineering Contradiction:
Improvestructural stabilityVSAvoidease of repair
Core Design Contradiction:
Stability of the object's compositionVSEase of repair

Solution Approach 1:

The control module is designed as a separate, detachable component from the main body housing, allowing it to be independently removed and replaced. This segmentation enables easy repair and maintenance of the control module without affecting the overall structural stability of the apparatus, as the module can be accessed and serviced independently.

Inventive Principle:
Principle #1Segmentation

3Productivity

If multiple complete PCR systems are deployed for simultaneous testing, then the productivity is improved, but the loss of substance and cost increase

Engineering Contradiction:
Improvesimultaneous testing capabilityVSAvoidcost
Core Design Contradiction:
ProductivityVSLoss of substance

Solution Approach 1:

The patent merges multiple PCR modules into a single apparatus that shares common infrastructure including the control module, display panel, power supply, and housing. This consolidation allows simultaneous testing of multiple samples while avoiding the duplication of expensive components, thereby reducing overall cost and resource consumption compared to deploying multiple separate PCR systems.

Inventive Principle:
Principle #5Merging (Combining)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enables simultaneous PCR inspections on multiple samples with reduced maintenance costs and lower product prices by integrating multiple modules with a single control unit and a rotatable display panel.

Implementation Method 1

The heating/cooling module 150 is configured to heat or cool the biochip 140

Methodology Applied
Scientific EffectHeating: Heating

Implementation Method 2

The heating/cooling module 150 is configured to heat or cool the biochip 140

Methodology Applied
Scientific EffectCooling: Cooling

Implementation Method 3

The light source module 160 includes a plurality of LEDs 161

Methodology Applied
Scientific EffectLight emission from LED: Light Emitting Diode

Implementation Method 4

The detection module 170 serves to detect fluorescence radiated from the biochip 140

Methodology Applied
Scientific EffectFluorescence detection: Fluorescence

Data Source

PatentUS12472503B2Modular type multi-plex PCR apparatus
Publication Date: 2025.11.18 GENESYSTEM CO LTD
  • US12472503B2 patent drawing
  • US12472503B2 patent drawing
  • US12472503B2 patent drawing

AI summary

The present disclosure relates to a modular simultaneous diagnosis PCR system, in which a plurality of seating grooves, in which biochips are seated, is formed in an upper surface of a single main body housing, a plurality of heating/cooling modules and a plurality of light source modules are installed in the main body housing so as to correspond to the seating grooves, a plurality of cover members including detection modules corresponding to the seating grooves is installed on an upper surface of the main body housing so as to be rotatable upward or downward, and a PCR inspection is simultaneously performed on samples accommodated in multiple biochips by controlling the plurality of heating/cooling modules, the plurality of light source modules, and the plurality of detection modules in an integrated manner by using a single control module installed in the main body housing.