Modular sample store

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Solution Overview

Problem

Existing sample storage systems face challenges in maintaining low temperatures for biological and biochemical samples, leading to issues such as ice crystal growth, warming of samples, and cumbersome handling procedures, especially when dealing with large numbers of samples.

Innovation Solution

A modular sample store with a temperature-controlled storage area and a motorized robot system that allows for efficient storage and retrieval of samples within a controlled temperature range of -20°C to -90°C, utilizing integrally formed cubic vat modules with polymer foam insulation and a modular design for scalability.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of operation

If samples are stored at -18°C in commercially available freezers, then storage is simple and accessible, but ice crystal growth occurs leading to sample destruction

Engineering Contradiction:
Improvestorage simplicityVSAvoidsample integrity
Core Design Contradiction:
Ease of operationVSReliability

Solution Approach 1:

The patent changes the storage temperature parameter from -18°C to -80°C or lower, which fundamentally alters the physical state of water in samples and prevents ice crystal growth that occurs at higher temperatures, thereby maintaining sample integrity while preserving operational simplicity through automated systems

Inventive Principle:
Principle #35Parameter changes

2Reliability

If samples are stored in liquid nitrogen at -196°C, then ice crystal growth is prevented and sample integrity is maintained, but handling becomes cumbersome and requires dedicated safety measures

Engineering Contradiction:
Improvesample integrityVSAvoidhandling convenience
Core Design Contradiction:
ReliabilityVSEase of operation

Solution Approach 1:

The patent selects -80°C as an optimal temperature parameter that balances sample integrity (preventing ice crystal growth) with operational feasibility (avoiding liquid nitrogen's extreme handling requirements), achieving reliable storage without the safety measures and specialized training needed for cryogenic temperatures

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent introduces an automated robotic system as an intermediary between the storage system and human operators, allowing samples to be stored at optimal low temperatures while the robot handles all retrieval and manipulation tasks, eliminating the need for human personnel to directly handle extreme cold conditions

Inventive Principle:
Principle #24Intermediary (Mediator)

3Quantity of substance

If a large number of samples are stored in centralized facilities, then storage capacity is increased, but access time and retrieval efficiency decrease

Engineering Contradiction:
Improvestorage capacityVSAvoidretrieval time
Core Design Contradiction:
Quantity of substanceVSLoss of time

Solution Approach 1:

The patent replaces manual mechanical retrieval operations with an automated robotic system that uses computer-controlled movements, sensors, and automated handling mechanisms to rapidly locate and retrieve samples from large-scale storage facilities, dramatically reducing access time while maintaining high storage capacity

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

4Adaptability or versatility

If modular design is implemented for scalability, then system adaptability is improved, but device complexity increases

Engineering Contradiction:
ImprovescalabilityVSAvoidsystem complexity
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The patent divides the storage system into modular segments including standardized storage modules, robotic end-effectors, and control units that can be independently configured and scaled, allowing the system to adapt to different laboratory sizes and sample volumes while managing complexity through standardized interfaces and protocols

Inventive Principle:
Principle #1Segmentation

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The system provides efficient and reliable storage and retrieval of samples at controlled temperatures, minimizing ice crystal growth and warming, while allowing for easy scalability and maintenance, thus ensuring sample integrity and reducing handling time.

Implementation Method 1

a polymer foam material that provides fixation of the outside and inside liners to each other as well as thermal insulation of and reinforcement to the thus integrally formed cubic vat module sandwich construction

Methodology Applied
Scientific EffectThermal insulation: Thermal Insulation

Data Source

PatentUS10834918B2Modular sample store
Publication Date: 2020.11.17 BROOKS AUTOMATION INC
  • US10834918B2 patent drawing
  • US10834918B2 patent drawing
  • US10834918B2 patent drawing

AI summary

A modular sample store including a storage area; a service area; a transfer area; a motorized robot with a lifting device and at least one platform; and a controller. The sample store service area includes one integrally formed cubic vat module and the sample store storage area includes at least one integrally formed cubic vat module. Each one of the aforementioned vat modules includes an essentially horizontal vat floor and four joining vat walls that are connected to the vat floor and that are leaving an open vat space. The modular sample store also includes upper side walls and a cover plate to close the sample store. Each vat floor and vat wall includes an outside liner and an inside liner, which outside and inside liners in each case are separated by a clearance. This clearance is essentially filled with a polymer foam material that provides fixation of the outside and inside liners to each other as well as thermal insulation of and reinforcement to the thus integrally formed cubic vat module sandwich construction.