Molded Tissue Scaffold Container with Shape Memory Frame

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Solution Overview

Problem

Current tissue scaffold containers are large and inconvenient for application and carrying, posing challenges in portability, sterility, and stability during tissue engineering processes.

Innovation Solution

A molded container with a bag-shaped design featuring a shape memory frame and an inner support tube, including adjustable hooks and magnetic elements, which allows for adjustable, sterile, and stable tissue scaffold formation and handling.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of operation

If traditional large equipment containers are used for tissue scaffolds, then tissue scaffold formation can be achieved, but portability and ease of carrying deteriorate

Engineering Contradiction:
ImproveportabilityVSAvoidcontainer size
Core Design Contradiction:
Ease of operationVSVolume of moving object

Solution Approach 1:

The container is divided into multiple functional components: a flexible bag for containment, a shape memory frame for structural support, an inner support tube for scaffold formation, and a sealing part for closure. This segmentation allows each component to be optimized for its specific function while collectively achieving compact portability

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The inner support tube is disposed within the bag, and the shape memory frame is embedded in the bag, creating a nested structure where smaller components are contained within larger ones. This nesting approach minimizes the overall volume of the container while maintaining all necessary functional elements

Inventive Principle:
Principle #7Nested doll (Nesting)

2Reliability

If traditional containers are used for tissue scaffolds, then tissue scaffold formation can be achieved, but sterility is compromised

Engineering Contradiction:
ImprovesterilityVSAvoidconvenience
Core Design Contradiction:
ReliabilityVSEase of operation

Solution Approach 1:

The sealing part is designed to be removable from the bag, allowing the inner support tube and scaffold materials to be extracted in a sterile manner. This extraction approach enables sterility maintenance during critical operations while preserving overall convenience

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The bag is made from flexible material that can be sealed to maintain sterility, yet remains easy to handle and operate. The flexible nature allows for convenient manipulation while the sealing capability ensures sterile environment protection

Inventive Principle:
Principle #30Flexible shells and thin films

3Stability of the object's composition

If traditional containers are used for tissue scaffolds, then tissue scaffold formation can be achieved, but stability during processing deteriorates

Engineering Contradiction:
ImprovestabilityVSAvoidcontainer structure
Core Design Contradiction:
Stability of the object's compositionVSDevice complexity

Solution Approach 1:

The shape memory frame provides dynamic structural support that can adapt to different tissue scaffold configurations while maintaining stability. The frame's shape memory properties allow it to maintain a stable structure during processing yet be adjustable when needed

Inventive Principle:
Principle #15Dynamics

Solution Approach 2:

Multiple stabilizing functions are merged into the container structure: the shape memory frame provides structural stability, the inner support tube ensures scaffold formation stability, and the sealing part maintains environmental stability. This merging achieves comprehensive stability without requiring separate complex stabilization systems

Inventive Principle:
Principle #5Merging (Combining)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The container provides enhanced portability, adjustability, sterility, and stability, enabling efficient tissue scaffold formation and handling while maintaining a sterile environment, facilitating tissue engineering processes.

Implementation Method 1

a shape memory frame embedded in the bag

Methodology Applied
Scientific EffectShape memory effect: Shape Memory Alloy

Implementation Method 2

The magnetic elements may close or open the operation window thereabove by magnetic attraction or repellence forces

Methodology Applied
Scientific EffectMagnetic attraction: Magnetism

Implementation Method 3

The magnetic elements may close or open the operation window thereabove by magnetic attraction or repellence forces

Methodology Applied
Scientific EffectMagnetic repellence: Magnetism

Data Source

PatentUS10376330B2Molded container for tissue scaffolds
Publication Date: 2019.08.13 NAT CHENG KUNG UNIV
  • US10376330B2 patent drawing
  • US10376330B2 patent drawing
  • US10376330B2 patent drawing

AI summary

A molded container for a tissue scaffold is provided. The molded container comprises a bag made from a soft material, a shape memory frame, and an inner support tube. A sealing part is disposed on the opening of the bag, and an operation window is disposed on the lower part of the bag. The sealing part is closed when no external force is applied. The shape memory frame is embedded in the bag. At least two adjustable hooks are disposed on the ends of the shape memory frame. The inner support tube is disposed on the inner bottom of the bag and selectively penetrates a molded accommodation volume for forming a tissue scaffold. The length of the inner support tube is more than the length of the molded accommodation volume. Therefore, the molded container for a tissue scaffold has features of portability, adjustability, sterility, convenience, and stability.