Monk Fruit Sweetener Iron Supplement Formulation

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Solution Overview

Problem

Traditional iron supplements for infants and young children are often unpalatable, leading to nausea, vomiting, and noncompliance due to their unpleasant taste and alcohol content, which can result in inaccurate dosing and potential iron poisoning.

Innovation Solution

A non-nutritive sweetener derived from monk fruit, combined with natural flavorings like grape and raspberry, is used to create an iron supplement formulation that masks the unpleasant taste of polysaccharide iron complex, eliminating alcohol and maintaining stable blood glucose levels.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If traditional iron supplements are used, then iron deficiency can be treated, but the unpleasant taste and alcohol content cause nausea, vomiting, and noncompliance

Engineering Contradiction:
Improveiron deficiency treatment effectivenessVSAvoidunpleasant taste, alcohol content, nausea, vomiting
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent removes alcohol from the formulation entirely, extracting the harmful component that causes nausea and vomiting in traditional iron supplements, while retaining the therapeutic iron content

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The patent introduces flavor掩蔽 agents as intermediaries that mask the unpleasant taste of iron supplements, making them palatable for infants and children without affecting the iron content or therapeutic effectiveness

Inventive Principle:
Principle #24Intermediary (Mediator)

2Reliability

If polysaccharide iron complex is used, then iron absorption is improved, but the formulation contains alcohol and has unpleasant taste leading to inaccurate dosing

Engineering Contradiction:
Improveiron absorptionVSAvoiddosage accuracy
Core Design Contradiction:
ReliabilityVSMeasurement precision

Solution Approach 1:

The patent extracts and eliminates alcohol from the polysaccharide iron complex formulation, removing the component that interferes with physiological functions and complicates dosing in infants

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The patent employs flavor掩蔽 agents as intermediaries that enable accurate dosing by making the formulation palatable, preventing spitting out and ensuring the full dosage is consumed by infants and children

Inventive Principle:
Principle #24Intermediary (Mediator)

3Reliability

If conventional iron fortificants are used, then iron deficiency can be corrected, but safety concerns arise from intolerance and accidental overdosing

Engineering Contradiction:
Improveiron deficiency correctionVSAvoidintolerance, accidental overdosing, hospitalization risk
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent changes the chemical composition parameters by using iron complexes with controlled iron content and eliminating alcohol, reducing toxicity risks while maintaining therapeutic effectiveness

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent introduces flavor掩蔽 agents as intermediaries that prevent vomiting and ensure accurate dosing, thereby preventing accidental overdosing and reducing hospitalization risks in children

Inventive Principle:
Principle #24Intermediary (Mediator)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The formulation significantly improves palatability, reducing gag reflex and vomiting, allowing for accurate dosing and safer administration of iron supplements without altering blood glucose levels or causing toxicity.

Implementation Method 1

A non-nutritive sweetener derived from monk fruit, combined with natural flavorings like grape and raspberry, is used to create an iron supplement formulation that masks the unpleasant taste of polysaccharide iron complex

Methodology Applied
Scientific EffectTaste masking:

Implementation Method 2

A non-nutritive sweetener derived from monk fruit... does not disrupt blood glucose levels and allows for a formulation of an iron supplement that avoids alcohol

Methodology Applied
Scientific EffectNon-nutritive sweetening:

Data Source

PatentUS20220312813A1Formulation for iron supplements
Publication Date: 2022.10.06 MONSIVAIS PATRICK
  • US20220312813A1 patent drawing

AI summary

An iron supplement nutritional formulation for infants and adults is provided using a non-nutritive sweetener including an extract from monk fruit (Siraitia grosvenorii) in combination with a polysaccharide iron complex. The formulation improves the taste and palatability of the supplement, thereby increasing the dosage accuracy within children and infants who tend to spit out or regurgitate other forms of polysaccharide iron complexes.