Monoblock Elastomeric Pre-filled Container for Sterile Medical Dispensing

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Solution Overview

Problem

Current pre-filled containers for medical substances are costly due to multiple parts requiring assembly, struggle with consistent droplet formation during use, and lack an affordable, sterile system that keeps the needle and product separate during shipping and storage, while also preventing reuse.

Innovation Solution

A pre-filled container with a squeezable activation compartment and a dispensing compartment connected by a movable activator element, which isolates the contents until activation, ensuring accurate and sterile dispensing, and featuring a design that prevents reuse by locking the activator element in an open position.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If pre-filled containers use multiple parts requiring assembly with metal components, then the isolation and sterility of substances are ensured, but the manufacturing cost considerably increases

Engineering Contradiction:
Improveisolation and sterilityVSAvoidmanufacturing cost
Core Design Contradiction:
ReliabilityVSEase of manufacture

Solution Approach 1:

The patent merges multiple separate components (container body, activator, sealing elements, metal components) into an integrated monoblock structure made of elastomeric material. The container body and activator are formed as a single piece through injection molding, eliminating the need for separate metal components and complex assembly processes while maintaining the hermetic sealing and isolation functions.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The elastomeric material serves multiple functions simultaneously: it provides structural integrity, hermetic sealing, isolating barriers, and the activating mechanism. The monoblock design integrates the container body, activator element, sealing elements, and dispensing control into a single multi-functional component that replaces multiple specialized parts.

Inventive Principle:
Principle #6Universality (Multi-functionality)

2Reliability

If pre-filled containers use multiple parts requiring assembly, then the sterility and isolation are ensured, but the device complexity increases

Engineering Contradiction:
ImprovesterilityVSAvoidnumber of parts
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent combines multiple discrete parts into a single monoblock elastomeric structure. The container body, activator, sealing elements, and dispensing mechanism are all integrated into one piece, reducing the number of parts from multiple components to a single unit while maintaining sterility through the elastomeric material's inherent properties and molded-in sealing features.

Inventive Principle:
Principle #5Merging (Combining)

3Reliability

If the container keeps needle and product separate during shipping, then sterility is maintained, but the mechanism becomes complex and costly

Engineering Contradiction:
ImprovesterilityVSAvoidmanufacturing cost
Core Design Contradiction:
ReliabilityVSEase of manufacture

Solution Approach 1:

The needle is nested within the elastomeric container body in a retracted position, surrounded by the elastomeric material that acts as both container and protective sheath. This nesting arrangement keeps the needle sterile and isolated from the external environment during shipping and storage, while the elastomeric material provides continuous sealing without requiring separate sealing components.

Inventive Principle:
Principle #7Nested doll (Nesting)

4Object-affected harmful factors

If the container is designed for single-use with non-reusability, then contamination is prevented, but the device requires additional locking mechanisms

Engineering Contradiction:
Improvecontamination preventionVSAvoidlocking mechanism
Core Design Contradiction:
Object-affected harmful factorsVSDevice complexity

Solution Approach 1:

The elastomeric material is pre-configured with irreversible deformation characteristics that automatically prevent reuse after activation. Once the activator is pressed and the seal is broken, the elastomeric material undergoes permanent deformation that makes re-sealing impossible, built into the material properties rather than requiring additional mechanical locking components.

Inventive Principle:
Principle #10Preliminary action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The container provides a cost-effective, sterile, and easy-to-use solution for dispensing medical substances as a spray, ensuring accurate dosing, preventing contamination, and securely preventing reuse, while maintaining sterility until activation.

Implementation Method 1

The activator element passes from a closed position, in which it hermetically and/or fluid-dynamically isolates the contents of the activation compartment from the contents of the dispensing compartment, to an open position, in which it puts them into communication

Methodology Applied
Scientific EffectMechanical Force: Mechanical Force

Implementation Method 2

The activation compartment is configured so that when squeezed, it interferes with the activator element to allow the movement thereof

Methodology Applied
Scientific EffectCompression: Compression

Data Source

PatentEP4120989B1Pre-filled container, method of use and related production method
Publication Date: 2025.04.30 BREVETTI ANGELA SRL
  • EP4120989B1 patent drawingFigure 1A~1E
  • EP4120989B1 patent drawingFigure 2A~4
  • EP4120989B1 patent drawingFigure 5A~6B

AI summary

This invention relates to a container (1 ) which is pre-filled or pre- fillable with one or more substances, such as a medical liquid and similar, comprising a squeezable activation compartment (2) intended to contain said one or more substances, a dispensing compartment (3) including a first portion (31 ) equipped with at least one dispensing member (311, 312, 314) of said one or more substances, and a second portion (32), wherein said second portion (32) of said dispensing compartment (3) and said activation compartment (2) are fluid-dynamically connected, and an activator element (4) arranged inside said container (1 ). This invention also relates to a method for dispensing at least one substance by means of a container (1 ), and to a production method of a container (1 ).