Monolysinate Preparation in Aqueous Solution for High Purity
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Solution Overview
Problem
Existing methods for producing amino acid chelate compounds, particularly those involving lysine, are plagued by impurities from mechanical activation processes, equipment corrosion, and unsuitable reaction conditions, leading to low purity and high costs.
Innovation Solution
A method involving a liquid reaction mixture of lysine and a metal salt, dissolved in an aqueous solution, followed by conversion and drying to produce monolysinate compounds, which are essentially free of impurities and corrosion-causing residues, using metal salts like manganese, iron, or zinc sulfates.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Productivity
If mechanical activation methods (ball mills, vibrating mills) are used to produce amino acid chelate compounds, then reaction efficiency is improved, but abrasion impurities are generated and equipment corrosion occurs
Solution Approach 1:
The patent replaces mechanical activation methods (ball mills, vibrating mills) with a chemical reaction approach using aqueous lysine solution and metal salts. The reaction proceeds through dissolution and chemical interaction in liquid phase, eliminating mechanical stress that causes abrasion and equipment wear, while maintaining effective reaction efficiency through solution-phase chemistry.
Solution Approach 2:
The patent changes the physical state parameters of the reactants from solid (in mechanical activation) to aqueous solution. By dissolving lysine and metal salts in water, the reaction occurs in liquid phase with improved contact between reactants, eliminating the need for mechanical activation and its associated problems while enhancing reaction efficiency through molecular-level mixing.
2Speed
If solid-state reaction with mechanically activated metal compounds is used, then reaction speed is improved, but equipment corrosion and abrasion residues contaminate the product
Solution Approach 1:
The patent changes the reaction medium from solid state to aqueous solution. Metal salts and lysine are dissolved in water, creating a liquid-phase reaction environment that eliminates mechanical activation requirements. This maintains fast reaction kinetics through enhanced molecular diffusion and contact while completely avoiding equipment corrosion and abrasion that plague solid-state mechanical processing.
Solution Approach 2:
The patent replaces mechanical activation and solid-state reaction with solution-phase chemical reaction. The aqueous medium enables rapid mixing and molecular-level contact between reactants, achieving fast reaction speeds without mechanical stress on equipment, thereby eliminating corrosion and abrasion contamination sources.
3Ease of manufacture
If fermentation-derived lysine sulfate is used as starting material, then availability is improved, but fermentation byproduct impurities are introduced
Solution Approach 1:
The patent extracts or removes the problematic fermentation byproduct impurities by starting with highly pure synthetic lysine (>99% purity) instead of fermentation-derived lysine sulfate. This extraction of the impurity source at the beginning of the process ensures that no fermentation contaminants are present to interfere with chelate formation or require subsequent removal steps.
Solution Approach 2:
The patent changes the purity parameter of the starting lysine material from typical fermentation product levels (with undefined byproducts) to >99% pure synthetic lysine. This parameter change eliminates the source of fermentation impurities while maintaining ease of manufacture through availability of commercial synthetic lysine.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The method produces highly pure monolysinate compounds with reduced impurities and lower production costs, avoiding equipment corrosion and maintaining product integrity for use in animal feed and other applications.
Implementation Method 1
provision of a liquid reaction mixture in which lysine and a metal salt are dissolved
Implementation Method 2
drying of the liquid reaction mixture to obtain the monolysinate compound
Data Source
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AI summary
The invention relates to a process for the production of a monolysinate compound (200, 300, 400, 500, 600, 700, 800, 900). The process comprises providing (502) a liquid reaction mixture (810) in which lysine (802) and a metal salt (404) are dissolved; reacting the lysine dissolved in the reaction mixture and the metal salt to form the monolysinate compound; and drying the liquid reaction mixture to obtain the monolysinate compound.