Antibacterial Mouthrinse with Proboscidea jussieui Extract
Find Innovative SolutionsGenerate Solutions
Solution Overview
Problem
Current chemical mouthrinse compositions, while effective, face issues such as bacterial resistance, side effects like taste alteration, and teeth staining, necessitating the development of alternative, safe, and cost-effective oral care solutions derived from natural resources.
Innovation Solution
A mouthrinse composition comprising an ethanolic extract of Proboscidea jussieui leaves, fluoride, propylene glycol, and a sugar alcohol like Sorbitol, with optional flavoring agents like menthol, providing antibacterial activity against bacteria like Enterococcus faecalis and Streptococcus mutans.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If chemical mouthrinse compositions (e.g., chlorhexidine) are used, then antibacterial effectiveness is improved, but side effects such as bacterial resistance, taste alteration, and teeth staining occur
Solution Approach 1:
The patent changes the chemical composition parameters by replacing synthetic antiseptics with natural plant extracts (Proboscidea jussieui, Plectranthus amboinicus, Ocimum sanctum) at optimized concentrations. This substitution maintains antibacterial effectiveness while eliminating harmful side effects associated with chemical mouthwashes, including bacterial resistance, taste alteration, and teeth staining.
Solution Approach 2:
The invention uses a composite formulation combining multiple natural plant extracts (Proboscidea jussieui, Plectranthus amboinicus, Ocimum sanctum) with fluoride and essential oils. This composite approach synergistically enhances antibacterial activity while providing comprehensive oral care benefits without the harmful effects of single chemical agents like chlorhexidine.
2Object-affected harmful factors
If natural resource-based mouthrinse compositions are used, then safety and cost-effectiveness are improved, but antibacterial effectiveness may be reduced
Solution Approach 1:
The patent merges multiple natural plant extracts (Proboscidea jussieui, Plectranthus amboinicus, Ocimum sanctum) with fluoride and essential oils in a synergistic formulation. This combination consolidates the antibacterial properties of individual plants while adding fluoride for enamel protection and essential oils for enhanced antimicrobial activity, achieving effectiveness comparable to chemical mouthwashes without their harmful side effects.
Solution Approach 2:
The invention optimizes the concentration parameters of each natural extract and additive to maximize antibacterial effectiveness. By carefully controlling the ratios of plant extracts, fluoride content, and essential oil concentrations, the formulation achieves reliable antibacterial activity while maintaining safety and cost-effectiveness.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The composition effectively inhibits bacterial growth and infection, offering a safe and cost-effective alternative to chemical mouthwashes, reducing the risk of bacterial resistance and side effects, while maintaining oral health.
Implementation Method 1
The composition effectively inhibits bacterial growth and infection, offering a safe and cost-effective alternative to chemical mouthwashes
Implementation Method 2
an exemplary fluoride component, and propylene glycol... an exemplary mouthrinse composition may further comprise an exemplary sugar alcohol
Implementation Method 3
propylene glycol may have a concentration between about 0.7% (w/v) and 1.3% (w/v)
Implementation Method 4
An exemplary sugar alcohol may comprise Sorbitol with a concentration between about 10% (w/v) and 20% (w/v)
Implementation Method 5
An exemplary flavoring agent may comprise menthol with a concentration between about 0.07% (w/v) and 0.5% (w/v)
Data Source
AI summary
A mouthrinse composition comprising an ethanolic extract of Proboscidea jussieui leaves with a concentration between 0.7% (w/v) and 1.3% (w/v), a fluoride component with a concentration between 0.02% (w/v) and 0.08% (w/v), and propylene glycol with a concentration between 0.7% (w/v) and 1.3% (w/v).