Movable Detection Component for Microfluidic Alignment

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Solution Overview

Problem

Microfluidic chip-based biochemical detection systems face challenges in accurate alignment and spatial crosstalk due to the small diameter of detection holes, requiring precise alignment and motion scanning to identify substance content effectively.

Innovation Solution

A detection apparatus with a movable detection component and a U-shaped or C-shaped connection structure, incorporating a light-emitting device, optical collimation, and a photoelectric converter, allows for precise alignment and efficient signal transmission, reducing assembly difficulties and increasing detection accuracy.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Volume of moving object

If a microfluidic chip with small diameter detection holes is used, then the device size is reduced and portability is improved, but alignment precision deteriorates and spatial crosstalk increases

Engineering Contradiction:
Improvedevice sizeVSAvoidalignment precision
Core Design Contradiction:
Volume of moving objectVSManufacturing precision

Solution Approach 1:

The detection device is segmented into independent functional modules: a movable detection component containing signal transmitters and receivers, a separate object receiving part, and a connection part. This modular segmentation allows each module to be optimized independently, enabling precise alignment mechanisms to be implemented in the detection component while maintaining the overall compact size of the microfluidic chip.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The detection component is designed to be movable relative to the object receiving part, allowing dynamic adjustment of the detection signal transmission path. This dynamic configuration enables precise alignment between signal transmitters, receivers, and detection holes through relative motion, thereby improving alignment precision without increasing the overall device volume.

Inventive Principle:
Principle #15Dynamics

2Manufacturing precision

If the detection component is made movable to improve alignment, then alignment precision is improved, but device complexity increases

Engineering Contradiction:
Improvealignment precisionVSAvoidstructural complexity
Core Design Contradiction:
Manufacturing precisionVSDevice complexity

Solution Approach 1:

The movability is implemented along a specific dimension (the transmission path direction) rather than full three-dimensional movement. The detection component moves only in the direction necessary to align the signal transmission path with the detection holes, reducing the complexity of the motion control mechanism while achieving the required alignment precision.

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

Solution Approach 2:

A connection part serves as an intermediary between the movable detection component and the stationary object receiving part. This connection structure facilitates the relative motion while maintaining structural integrity and signal transmission, simplifying the overall mechanism by providing a dedicated interface for the movable connection without requiring complex coupling mechanisms.

Inventive Principle:
Principle #24Intermediary (Mediator)

3Measurement precision

If signal transmitters and receivers are spaced apart to detect through the chip, then detection capability is improved, but spatial crosstalk increases

Engineering Contradiction:
Improvedetection capabilityVSAvoidspatial crosstalk
Core Design Contradiction:
Measurement precisionVSObject-generated harmful factors

Solution Approach 1:

The detection device employs local optimization of the signal transmission path by precisely aligning each signal transmitter and receiver pair with specific detection holes. This localized precision alignment ensures that signals pass through intended detection regions only, minimizing spatial crosstalk while maintaining detection capability across multiple channels.

Inventive Principle:
Principle #3Local quality

Solution Approach 2:

The movable detection component enables dynamic adjustment of the signal transmission path to achieve precise alignment with individual detection holes. By dynamically positioning the transmitters and receivers, the system can selectively activate specific detection channels and prevent signals from adjacent channels from interfering, thereby reducing spatial crosstalk while maintaining detection capability.

Inventive Principle:
Principle #15Dynamics

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The apparatus achieves accurate and efficient biochemical detection with reduced spatial crosstalk and improved alignment, enabling precise measurement of substance content in microfluidic chips.

Implementation Method 1

the signal transmitter comprises a light-emitting device to transmit an optical signal as the detection signal

Methodology Applied
Scientific EffectLight emission: Light Emitting Diode

Implementation Method 2

the optical collimation component is configured to collimate the optical signal into parallel light

Methodology Applied
Scientific EffectOptical collimation: Lens

Implementation Method 3

the photoelectric converter is configured to convert the received optical signal into a detection result signal, and to output the detection result signal

Methodology Applied
Scientific EffectPhotoelectric conversion: Photoelectric Effect

Implementation Method 4

the light filter element is arranged in the transmission path, and allows the optical signal with a given wavelength in the received optical signal to pass through

Methodology Applied
Scientific EffectOptical filtering: Filter (optical)

Data Source

PatentUS12140531B2Detection device and detection method
Publication Date: 2024.11.12 BEIJING BOE HEALTH TECH CO LTD
  • US12140531B2 patent drawing
  • US12140531B2 patent drawing
  • US12140531B2 patent drawing

AI summary

A detection apparatus and a detection method. The detection apparatus includes: a main body, a detection assembly, and a detection object receiving portion. The detection assembly includes: a signal transmitter, configured to transmit detection signals; a signal receiver, configured to receive at least part of the detection signals transmitted by the signal transmitter; and a detection connection portion, connected to the signal transmitter and the signal receiver and causing the signal transmitter and the signal receiver to be spaced from each other by the detection connection portion. The detection object receiving portion is configured to receive a detection object. The detection object receiving portion and the detection assembly are relatively movably arranged on the main body so as to allow the detection object received by the detection object receiving portion to be located in a transmission path of the detection signals between the signal transmitter and the signal receiver.