Movable Needle Units for Cell Transplantation Depth Control

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Solution Overview

Problem

Existing cell transplantation devices face challenges in maintaining precise placement depth of cell groups due to the application of pressing and tensile forces during needle insertion and withdrawal, leading to deviations in the actual placement depth from the planned depth, which affects the survival and activity of the cell groups.

Innovation Solution

A cell transplantation device with movable units that independently control the movement and operation of multiple needles, allowing for synchronized penetration and withdrawal at different timings to reduce the force applied to the target site, thereby minimizing deviations in placement depth.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If multiple needles are inserted and withdrawn simultaneously at close range, then transplantation efficiency is improved, but pressing force and tensile force on the target site increase causing expansion and contraction, leading to large deviation in actual placement depth from planned depth

Engineering Contradiction:
Improvetransplantation efficiencyVSAvoidplacement depth precision
Core Design Contradiction:
ProductivityVSManufacturing precision

Solution Approach 1:

The plurality of needles are divided into multiple movable units, where each movable unit can be moved independently along the extending direction of the needles. This segmentation allows different needles to be inserted and withdrawn at different timings, reducing the simultaneous mechanical stress on the target site while maintaining collective transplantation capability.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The movable units are configured to be movable along the extending direction of the needles, enabling dynamic control of needle insertion and withdrawal timing. This dynamic adjustment reduces the pressing force and tensile force applied to the target site during the procedure, thereby minimizing tissue expansion and contraction that would cause depth deviation.

Inventive Principle:
Principle #15Dynamics

2Productivity

If the number of needles is increased, then collective transplantation of multiple cell groups is improved, but pressing force and tensile force on the target site increase causing tissue expansion and contraction

Engineering Contradiction:
Improvecollective transplantation capabilityVSAvoidpressing force and tensile force on target site
Core Design Contradiction:
ProductivityVSObject-affected harmful factors

Solution Approach 1:

By dividing the plurality of needles into multiple movable units with independent movement capability, the system can manage the mechanical load on the target site. Each movable unit can be operated separately, distributing the pressing and tensile forces over time rather than applying them all simultaneously, thus reducing tissue deformation.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The movable units are operated in a periodic or sequential manner rather than all at once. This periodic action allows the tissue to partially recover between needle insertions, reducing cumulative pressing force and tensile force effects, thereby minimizing expansion and contraction of the target site.

Inventive Principle:
Principle #19Periodic action

3Ease of operation

If needles are inserted and withdrawn at the same time, then operation simplicity is improved, but deviation of puncture depth from planned depth occurs due to tissue expansion and contraction

Engineering Contradiction:
Improveoperation simplicityVSAvoidpuncture depth accuracy
Core Design Contradiction:
Ease of operationVSManufacturing precision

Solution Approach 1:

The system provides dynamic control over needle insertion and withdrawal through independently movable units. While this adds some operational complexity, it enables precise control over the timing of each needle's insertion and withdrawal, allowing the operator to minimize tissue deformation while maintaining reasonable operational simplicity through coordinated movement.

Inventive Principle:
Principle #15Dynamics

Solution Approach 2:

The movable units can be positioned and prepared in advance before needle insertion begins. This preliminary positioning allows for optimized insertion sequences that minimize tissue deformation, and the system can be pre-configured to automate the coordinated movement, reducing the actual operational complexity during the procedure.

Inventive Principle:
Principle #10Preliminary action

Data Source

PatentEP4104903B1Transfer device for living body
Publication Date: 2025.04.02 TOPPAN INC
  • EP4104903B1 patent drawingFigure 1~2
  • EP4104903B1 patent drawingFigure 3~4
  • EP4104903B1 patent drawingFigure 5~6

AI summary

A transfer device for a living organism for placing an object in a living organism comprises a plurality of movable units. Each movable unit comprises one or more needles extending in a first direction. Each needle has a cylindrical shape capable of storing the object therein. Each movable unit is movable in the first direction.