Analyte Detection Device With Movable Receiving Chamber
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Solution Overview
Problem
Current rapid diagnosis devices for analyte detection in liquid samples, such as urine and saliva, often require professional testing and may not facilitate timely on-site detection, especially for samples like those from 'drugged drivers', and existing collection methods are not optimized for efficient fluid communication and sample processing.
Innovation Solution
A device with a receiving chamber and a detection chamber that can move between non-fluid communication and fluid communication positions, allowing for the controlled flow of liquid samples to the detection chamber, which includes a mechanism for mixing with a treatment solution and using an absorbent element to lock and align with the detection chamber for efficient analyte detection.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Ease of operation
If a syringe-type fluid sampling device is used, then sample collection is convenient and portable, but the device complexity increases and fluid communication control becomes difficult
Solution Approach 1:
The device is divided into separate functional modules: a receiving chamber for sample collection, a detection chamber for analysis, and a testing element. This segmentation allows each component to perform its specific function independently, simplifying the overall device structure while maintaining ease of operation for sample collection.
Solution Approach 2:
The receiving chamber is designed to be movable between a first position (not in fluid communication with the detection chamber) and a second position (in fluid communication). This dynamic positioning enables controlled fluid transfer without requiring complex valves or pumps, reducing device complexity while maintaining operational convenience.
2Speed
If the receiving chamber is always in fluid communication with the detection chamber, then sample detection is fast, but sample contamination and premature reaction occur
Solution Approach 1:
The receiving chamber transitions from a static to a dynamic design, moving between sealed (first position) and open (second position) states. This enables the system to maintain sample integrity during collection and transport, then rapidly initiate detection when needed, balancing speed and reliability.
Solution Approach 2:
The sample is collected and prepared in the receiving chamber in advance, kept sealed to prevent contamination. The chamber is pre-positioned ready for rapid transfer to the detection chamber, enabling fast detection initiation without compromising sample integrity during the preparation phase.
3Measurement precision
If professional testing agency processing is used, then detection accuracy is high, but detection time is long and on-site detection is not feasible
Solution Approach 1:
The device merges sample collection, sample preparation, and detection functions into a single integrated portable unit. The testing element in the detection chamber performs analysis directly on the sample, eliminating the need for external laboratory equipment and personnel, thereby enabling accurate on-site detection without time loss.
Solution Approach 2:
The device is designed for self-contained operation with all necessary components (receiving chamber, detection chamber, testing element) integrated into one unit. The system performs detection autonomously without requiring professional testing agency processing, achieving both high accuracy and rapid on-site results.
4Productivity
If the receiving chamber is moved from first position to second position, then fluid communication is established for detection, but device operation complexity increases
Solution Approach 1:
The receiving chamber is designed to move between two fixed positions (first and second positions) along a defined path. This dynamic but constrained movement simplifies the operation to a single action (moving the chamber) while establishing fluid communication for detection, improving productivity without significantly increasing operational complexity.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
Enables efficient detection and quantification of analytes in liquid samples, allowing for timely and accurate results, particularly suitable for on-site drug detection scenarios, by ensuring proper fluid communication and sample processing.
Implementation Method 1
U.S. Pat. No. 5,376,337 discloses a saliva sampling device in which a piece of filter paper is used to collect saliva from the mouth of a subject and deliver saliva to an indicator reagent
Implementation Method 2
when the receiving chamber is located at the second position, the receiving chamber is in fluid communication with the detection chamber, and liquid in the receiving chamber flows to the detection chamber
Data Source
AI summary
The invention provides a device for detecting an analyte in a liquid sample. The device comprises a receiving chamber for receiving an absorbent element, wherein the absorbent element is used for collecting a liquid sample; and a detection chamber configured to receive a testing element, wherein the testing element is set to test an analyte in a liquid sample, the receiving chamber is provided with a first position and a second position, when the receiving chamber is located at the first position, the receiving chamber is not in fluid communication with the detection chamber, and when the receiving chamber is located at the second position, the receiving chamber is in fluid communication with the detection chamber.