4D MR Flow Analysis via Automatic Valve Tracking

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Solution Overview

Problem

Current MR cardio imaging techniques face challenges in accurately characterizing blood flow patterns due to operator dependency, high error rates, and limited signal-to-noise ratio, particularly in dynamic cardiac environments, leading to inaccurate flow estimations and diagnosis.

Innovation Solution

The implementation of a computer-based method using axial cine MR image data for tracking valve locations during the cardiac cycle, which reduces operator interaction and enhances accuracy by employing volumetric data for valve tracking, allowing for the reformatting of three-directional velocity information into one-directional data for bi-dimensional flow analysis.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If 2D phase-contrast MR imaging planes are used for flow analysis, then flow quantification can be performed, but operator dependency and planning errors increase leading to reduced reliability

Engineering Contradiction:
Improveflow quantification accuracyVSAvoiddiagnosis reliability
Core Design Contradiction:
Measurement precisionVSReliability

Solution Approach 1:

The system performs automatic valve plane detection and tracking using algorithms that identify anatomical structures and calculate optimal analysis planes without operator intervention. The computer system automatically determines valve locations, orientations, and tracking throughout the cardiac cycle, eliminating manual planning errors and operator dependency while maintaining measurement precision.

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The manual mechanical process of operator-based plane planning is replaced with an automated computational system that uses image processing algorithms, coordinate transformations, and computer vision techniques to detect valve structures and calculate analysis planes automatically, thereby improving reliability without sacrificing measurement accuracy.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

2Area of stationary object

If multiple long-axis cine acquisitions are performed for valve tracking, then anatomical coverage is improved, but acquisition time and complexity increase

Engineering Contradiction:
Improveanatomical coverageVSAvoidacquisition time
Core Design Contradiction:
Area of stationary objectVSLoss of time

Solution Approach 1:

The system merges multiple acquisition sequences (cine MR data and 4D flow data) into a unified analysis framework. By combining data from different sequences and using automatic valve detection algorithms, the system achieves comprehensive anatomical coverage without requiring separate manual planning for each sequence, thereby reducing total acquisition time while maintaining coverage.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The automatic valve detection and tracking system serves multiple functions simultaneously: it works across different MR sequences (cine and 4D flow), handles multiple valves, performs temporal tracking throughout the cardiac cycle, and generates analysis planes for flow quantification. This multi-functional approach eliminates the need for separate specialized acquisitions for each purpose.

Inventive Principle:
Principle #6Universality (Multi-functionality)

3Measurement precision

If manual valve tracking is performed on each time frame, then accurate flow estimation is achieved, but analysis time and operator workload increase significantly

Engineering Contradiction:
Improveflow estimation accuracyVSAvoidanalysis efficiency
Core Design Contradiction:
Measurement precisionVSProductivity

Solution Approach 1:

The system performs automatic valve tracking throughout the cardiac cycle using computational algorithms that detect valve structures in each time frame without operator intervention. The computer system automatically tracks valve positions, calculates orientations, and maintains temporal consistency, achieving accurate flow estimation while eliminating manual workload and significantly improving analysis efficiency.

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The system performs preliminary automatic valve detection and tracking during the post-processing stage before flow quantification is performed. By pre-calculating valve positions, orientations, and tracking trajectories using image processing algorithms, the system prepares all necessary information in advance, enabling accurate and efficient flow analysis without time-consuming manual tracking during the measurement phase.

Inventive Principle:
Principle #10Preliminary action

4Ease of operation

If static analysis planes are used in 2D MR flow, then acquisition is simplified, but through-plane motion occurs reducing measurement accuracy

Engineering Contradiction:
Improveacquisition simplicityVSAvoidflow measurement accuracy
Core Design Contradiction:
Ease of operationVSMeasurement precision

Solution Approach 1:

The system transitions from static analysis planes to dynamic tracking planes that automatically adapt to valve motion throughout the cardiac cycle. The computer system calculates time-varying analysis planes that follow valve positions in systole and diastole, maintaining perpendicularity to flow direction at each time point. This dynamic approach preserves acquisition simplicity while eliminating through-plane motion errors and improving measurement accuracy.

Inventive Principle:
Principle #15Dynamics

Solution Approach 2:

The system performs preliminary detection of valve positions and orientations at each time frame before conducting flow measurements. By pre-calculating the optimal analysis plane orientation based on detected valve anatomy, the system ensures that measurements are performed on correctly positioned planes without requiring manual adjustment during acquisition, thus maintaining simplicity while achieving high accuracy.

Inventive Principle:
Principle #10Preliminary action

Data Source

PatentUS10360674B2Flow analysis in 4D MR image data
Publication Date: 2019.07.23 PIE MEDICAL IMAGING
  • US10360674B2 patent drawing
  • US10360674B2 patent drawing
  • US10360674B2 patent drawing

AI summary

A method is provided for flow analysis in a target volume of a moving organ, which involves a sequence of first volumetric image data sets that include structural information and three-directional velocity information of the target volume and a sequence of second volumetric image data sets that include structural information of the target volume. The method involves tracking a feature of interest within the sequence of the second volumetric data sets, determining time varying spatial orientation of a plane containing the feature of interest in the sequence of the first volumetric image data sets by transferring the plane from the second volumetric image data sets to the first volumetric image data sets, reformatting the three-directional velocity information into one-directional velocity information on the plane, and performing bi-dimensional quantitative flow analysis using the one-directional velocity information. A corresponding apparatus and computer program are also disclosed and claimed.