Multi-Echo MR Image Reconstruction via Segmented Signal Models

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Solution Overview

Problem

Current techniques for determining magnetic resonance images with multiple spin species using chemical shift imaging multi-echo MR measurement sequences face challenges in achieving a balance between precision and speed, often resulting in either imprecise quantification due to simplifications or increased measurement time leading to movement artifacts.

Innovation Solution

A method involving the acquisition of a predetermined number of MR signals using a multi-echo MR measurement sequence, followed by the determination of two approximated MR images based on different approximative models that consider varying MR parameters, with a mean calculation to produce a final MR image, allowing for fast and precise determination of spin species content.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If comprehensive signal models considering multiple MR parameters (T2*, multispectral fat) are used, then measurement precision is improved, but measurement time increases leading to movement artifacts

Engineering Contradiction:
Improvefat/water separation precisionVSAvoidmeasurement time
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The patent segments the comprehensive signal model into multiple approximative models, each considering only a subset of MR parameters (e.g., one model considers T2* but simplifies fat spectrum, another considers multispectral fat but simplifies T2*). This allows parallel or sequential processing of simpler models to achieve comprehensive results without the full computational burden of a single comprehensive model, reducing measurement time while maintaining precision.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent applies partial action by using approximative models that consider only partial aspects of the full signal model (either T2* effects or multispectral fat, but not both in full detail simultaneously). This partial consideration of parameters in separate models allows faster processing while the combination of results achieves comprehensive accuracy.

Inventive Principle:
Principle #16Partial or excessive action

2Measurement precision

If additional MR parameters (T2*, multispectral fat) are considered in signal analysis, then measurement precision is improved, but device complexity increases

Engineering Contradiction:
ImproveMR parameter determination precisionVSAvoidsignal analysis complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent divides the complex signal analysis into multiple simpler approximative models, each handling a specific subset of parameters. This segmentation reduces the computational complexity of individual models while maintaining overall precision through the combination of their results.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent changes the parameter considerations across different approximative models - each model uses a simplified set of parameters compared to the comprehensive model. By varying which parameters are considered in each model, the overall system achieves comprehensive accuracy while individual models remain computationally simple.

Inventive Principle:
Principle #35Parameter changes

3Measurement precision

If more MR signals are acquired to improve precision, then measurement precision is improved, but measurement time increases

Engineering Contradiction:
Improvesolution stabilityVSAvoidmeasurement duration
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The patent uses a predetermined number of MR signals (not necessarily the maximum needed for full precision) and processes them through multiple approximative models. This partial acquisition combined with multiple processing approaches achieves stable solutions without requiring excessive measurement time for additional signals.

Inventive Principle:
Principle #16Partial or excessive action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach enables a rapid and accurate determination of MR images with minimal movement artifacts, allowing for flexible adaptation to breathing cycles and reduced measurement time, while maintaining precision in fat and water quantification and T2* estimation.

Implementation Method 1

Such techniques make use of the effect that the resonance frequency of the nuclear spins depends on the molecular or chemical environment. This is known as a chemical shift.

Methodology Applied
Scientific EffectChemical shift: Resonance

Implementation Method 2

Chemical shift imaging multi-echo magnetic resonance (MR) measurement sequences

Methodology Applied
Scientific EffectMagnetic resonance: Resonance

Implementation Method 3

an estimate can also be obtained for the T2* relaxation time that manifests in an echo time-dependent reduction of the signal strength

Methodology Applied
Scientific EffectT2* relaxation: Stress Relaxation

Data Source

PatentUS9568577B2Magnetic resonance method and apparatus for generating an image of a subject with two spin species
Publication Date: 2017.02.14 SIEMENS HEALTHINEERS AG
  • US9568577B2 patent drawing
  • US9568577B2 patent drawing
  • US9568577B2 patent drawing

AI summary

In a method and apparatus to determine a magnetic resonance image of an examination subject with at least two spin species by using a chemical shift imaging multi-echo MR measurement sequence, first approximated MR image is determined based on a first approximative model and of a second approximated MR image is determined based on a second approximative model, wherein the first and second approximative model respectively express an MR signal under consideration of one or more MR parameters, and wherein the first and second approximative model differ with regard to the consideration of at least one MR parameter. The MR image is determined from a mean calculation that depends on the first and second approximated MR image.